Sperm Count 31 million : Is it enough for pregnancy
In our latest blog post titled "Understanding Male Infertility: The Importance of Sperm Count," we delve into the various aspects of male infertility and its correlation with low sperm count. We explain what male infertility is, explore different grades of oligospermia (low sperm count), and discuss potential causes. We also highlight the questions one should ask themselves, what to expect during a doctor's examination, and additional tests that can be done to determine the cause. Furthermore, we touch upon the treatability of male infertility and the connection between sperm count and the chances of pregnancy. Lastly, we provide insights into assisted reproductive techniques and their success rates.
What is a normal sperm count?
A normal total sperm count is
39 million as per the WHO. For the purposes of this article we assume an ejaculatory volume of 3 ml.[1.5ml - 6ml].
What is Male Infertility
Male infertility is when a man and a woman try to have a baby by having unprotected sex for a whole year, but they can't make a baby. The woman is perfectly fine and can have babies, but the problem is with the man. About 20% of the time, the man is the only one to blame for not being able to make a baby.
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What is it called when sperm count is 31 million/ml?
This condition is called oligospermia or a low sperm count.
How is sperm count measured?
A sperm count is assessed by means of a
semen analysis test. In this test you are asked to provide a sample of your semen, and the lab uses special techniques to analyze the semen. The count is estimated by diluting the semen in a special diluent and then using a measurement chamber to visualize the sperms. A complex mathematical formula is employed to estimate the actual sperm count.
What is my grade of oligospermia?
Your sperm count is slightly lower than the normal range. Typically, a normal sperm count is considered to be above 39 million, and yours is at 31 million. This condition is called oligospermia, specifically mild oligospermia in your case. It means that the number of sperm in your semen is relatively low. While your count is slightly below the normal range, it is still within a mild range of oligospermia.
What are the causes of a sperm count of 31 million?
There are several different causes of oligospermia and they can be one of several categories including due to genetic factors, past cancer, secondary to other diseases, physical factors in the reproductive tract etc.
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Hyperthyroidism - Hyperestrogenic State
Hyperthyroidism is a condition where the thyroid gland produces an excessive amount of thyroid hormones. This leads to a hyperestrogenic state, meaning that there is an increase in estrogen levels in the body. This hormonal imbalance can affect sperm production and quality. To investigate this cause, a blood test can be done to measure the levels of thyroid hormones, such as TSH, T3, and T4.
Craniopharyngioma - Mass Effect Disrupts LH, FSH Production
Craniopharyngioma is a type of brain tumor that can cause a mass effect, meaning it puts pressure on nearby structures. In this case, it disrupts the production of LH (luteinizing hormone) and FSH (follicle-stimulating hormone) by the pituitary gland. These hormones are responsible for stimulating the testes to produce sperm. To investigate this cause, imaging tests like MRI or CT scans can be done to visualize the tumor and its effects on the pituitary gland.
Medications - Anabolic Steroids Suppress the Hypothalamo-Pituitary Axis
Anabolic steroids are synthetic substances that mimic the effects of testosterone. However, their use can suppress the hypothalamo-pituitary axis, which is responsible for regulating hormone production. This disruption can lead to a decrease in sperm count. To investigate this cause, a thorough review of the patient's medication history and potentially drug screening tests can be done.
Varicocele - Sloughing, Atrophy, Low Testosterone
Varicocele is a condition where the veins within the scrotum become enlarged. This can lead to sloughing (shedding) of sperm, testicular atrophy (shrinkage), and low testosterone levels. To investigate this cause, a physical examination of the scrotum can be done to detect any abnormalities, and ultrasound imaging can be used to assess the blood flow in the veins.
Hemochromatosis - Infiltrative Pituitary Disruption
Hemochromatosis is a genetic disorder where the body absorbs and stores too much iron. This excess iron can infiltrate the pituitary gland and disrupt its normal function. This disruption can affect sperm production. To investigate this cause, blood tests can be done to measure iron levels in the body, such as serum ferritin and transferrin saturation.
Infections - Prostatitis
Prostatitis is an infection or inflammation of the prostate gland. This infection can affect sperm production and quality. To investigate this cause, a physical examination of the prostate gland can be done to check for signs of infection, and a urine sample can be analyzed for the presence of bacteria or white blood cells.
Infections - Mumps Orchitis
Mumps orchitis is a complication of the mumps virus that affects the testicles. It can lead to inflammation and swelling, which can affect sperm production. To investigate this cause, a medical history review, physical examination, and potentially blood tests to detect mumps antibodies can be done.
Pituitary Adenoma - Exerts Mass Effect on the Gonadotrophs
A pituitary adenoma is a non-cancerous tumor that develops in the pituitary gland. It can exert a mass effect on the gonadotrophs, the cells responsible for producing LH and FSH. This disruption can lead to a decrease in sperm count. To investigate this cause, imaging tests like MRI or CT scans can be done to visualize the tumor and its effects on the pituitary gland.
Congenital Adrenal Hyperplasia - Unregulated ACTH Production
Congenital adrenal hyperplasia is a genetic disorder where there is an abnormality in the production of cortisol by the adrenal glands. This can result in excess adrenal androgens, which can suppress the pituitary gland and affect sperm production. To investigate this cause, blood tests can be done to measure hormone levels, such as ACTH, cortisol, and adrenal androgens.
Klinefelter's Syndrome - Chromosomal Abnormality
Klinefelter's Syndrome is a chromosomal abnormality where males have an extra X chromosome (XXY instead of XY). This can lead to hormonal imbalances and testicular dysfunction, resulting in reduced sperm production. Some men with this syndrome may be totally azoospermic (no sperm), while others may have oligospermia (low sperm count). To investigate this cause, genetic testing can be done to detect the presence of an extra X chromosome.
Questions to ask yourself for a sperm count of 31 million
Age at which you had puberty
Have you ever experienced any physical changes in your body, such as growing taller, developing facial hair, or experiencing voice changes, around the age when most boys go through puberty?
Surgery on testicles
Have you ever undergone surgery on your testicles? If so, please provide details.
Any trouble with sexual drive or function
Have you ever experienced any difficulties with your sexual drive or function?
Sexually transmitted infections
Have you ever been diagnosed or treated for any sexually transmitted infections in the past?
Infections of prostate or testicle
Have you ever experienced any infections or inflammation in your prostate or testicles?
Have you ever taken any medications, either currently or in the past, that could potentially affect your sperm count?
Use of alcohol, tobacco, illicit drugs
Have you ever consumed alcohol, tobacco, or illicit drugs? Please mention any instances, as it may help us understand the potential factors affecting your sperm count.
Systemic disease
Have you ever been diagnosed with or experienced any long-term health conditions that could affect your overall reproductive health, such as diabetes, high blood pressure, thyroid problems, or any other chronic diseases?
Environmental exposures, including radiation, pesticides, and occupational
Have you ever worked in a job or been exposed to radiation, pesticides, or other chemicals that could potentially affect your fertility?
Any Cancer diagnosis or treatment
Have you ever received a diagnosis of cancer or undergone any cancer treatments that might have affected your fertility?
What will be done during medical checkup for sperm count of 31 million?
Is your sexual development complete ? - Tanner stage
In order to determine if your sexual development is complete, the doctor will perform a Tanner stage examination. This examination involves looking at the physical changes in your body that occur during puberty. The doctor will assess the development of your genitals, the growth of body hair, and the changes in your voice. They may also ask about any changes you have noticed in your sexual desires or abilities. This examination will help the doctor understand if your sexual development is progressing normally or if there may be any underlying issues that need to be addressed.
Do you show signs of a mass in the brain? - Bitemporal hemianopsia (pituitary mass)
In order to determine if there is a mass in your brain causing bitemporal hemianopsia, the doctor will perform a thorough examination. This will involve asking you questions about your symptoms and medical history. The doctor may also conduct a physical examination, checking your vision and evaluating your overall neurological function. Additionally, the doctor might order further tests such as an MRI or CT scan to get a detailed picture of your brain and identify any abnormalities. Based on the findings, the doctor will be able to determine if there is indeed a mass in your brain that is causing the bitemporal hemianopsia.
Is your testicle size normal ? Reduced testicular volume (<15 cc)
The doctor will examine the size of your testicles to see if they are normal. This involves feeling the testicles with their hands. They will check if the size is smaller than what is considered normal, which is usually less than 15 cc. If the testicles are smaller, it could indicate a problem with sperm production. This could be one of the reasons for the low sperm count of 31.
Is there a mass in your testicle? - Testicular mass
The doctor will perform a physical examination to check for any abnormalities in the testicles. This may involve gently feeling the testicles to check for any lumps or masses. The purpose of this examination is to determine if there is any presence of a testicular mass, which could be a possible sign of a medical condition. It is important for the doctor to assess this as it may help in diagnosing any underlying issues and providing appropriate treatment if necessary.
Is the natural tube from testicles missing from either side? - Presence of vas deferens bilaterally
The doctor will examine the patient to see if the natural tube connecting the testicles is missing on either side. This tube is called the vas deferens and it plays a crucial role in carrying sperm. The examination will involve a physical examination of the patient's scrotum and groin area to look for any signs of absence or blockage of the vas deferens. The doctor may also order additional tests such as a semen analysis or imaging studies to further evaluate the condition. The results of this examination will help determine the cause of the patient's low sperm count and guide the appropriate treatment options.
Is there any cyst or swelling in the testicular sac ? - Presence of varicocele or other scrotal mass
The doctor will carefully examine the patient's testicular sac to check for any cyst or swelling. This involves feeling the scrotum with their hands to detect any abnormal lumps or masses. If there is a varicocele, which is a condition where the veins in the scrotum become enlarged, it can be felt during this examination. The doctor will gently apply pressure to the scrotum to assess for any discomfort or pain. This examination helps the doctor determine if there are any abnormalities in the testicles that could be affecting the patient's sperm count.
Are the testicles missing? - Presence of cryptorchidism or hypospadias
The doctor will check if the testicles are missing by physically examining the patient's groin area. They will gently feel for the presence of the testicles, which should be located inside the scrotum. If the testicles cannot be felt there, it could indicate a condition called cryptorchidism, where the testicles have not descended into the scrotum. In addition to this, the doctor will also check for the presence of hypospadias, a condition where the opening of the urethra is not at the tip of the penis, but is located on the underside. These examinations will help the doctor determine the possible reasons for the patient's sperm count of 31.
The doctor will check if there are any issues with the joints in the patient's hands. Specifically, they will examine the second and third knuckles to see if there is inflammation called synovitis.
Additionally, the doctor will look for any unusual changes in the color of the patient's skin, which may appear like a bronze or tan appearance. This could be a sign of liver disease or heart failure, a condition called hemochromatosis.
The examination will involve a visual inspection and possibly some physical tests to assess any joint problems or signs of liver or heart issues. This will help the doctor determine the best course of action for the patient's overall health.
Is the patient on muscle building steroids? Presence of marked muscle hypertrophy suggesting anabolic steroid use
The doctor will first visually examine the patient's muscles to see if there is an evident increase in size or bulk. They will look for any notable changes in muscle shape or definition that could suggest the use of muscle building steroids. Next, the doctor may ask the patient about their exercise routine, dietary habits, and any supplements or medications they are currently taking. They might also order additional tests, such as blood or urine analysis, to check for the presence of anabolic steroids in the patient's system. Based on the findings from these examinations and tests, the doctor will be able to determine if the patient is using muscle building steroids.
What additional tests are to be done for a sperm count of 31 million?
Step 1 : Test FSH, LH, Prolactin and Testosterone levels
To better understand the cause of infertility, the doctor has suggested testing the levels of four hormones: FSH, LH, Prolactin, and Testosterone. FSH (follicle-stimulating hormone) and LH (luteinizing hormone) play vital roles in sperm production and maturation. High levels of FSH may indicate a problem with the testicles, while high LH levels might suggest a problem with the pituitary gland. Prolactin is a hormone responsible for milk production, and elevated levels could be linked to infertility. Lastly, Testosterone is the male sex hormone, and checking its levels can help identify any hormonal imbalances that might contribute to the fertility issue. By analyzing these hormone levels, the doctor hopes to uncover any underlying issues causing the low sperm count.
Step 2 : Are FSH and LH lower than normal?
If a patient has a low sperm count of 31, it is possible that their FSH (follicle-stimulating hormone) and LH (luteinizing hormone) levels may also be lower than normal. This can indicate that the pituitary gland, which produces these hormones, is not functioning properly and not making enough hormones. To further investigate this, doctors may recommend an MRI scan to check for any issues with the pituitary gland. They may also look for systemic diseases like hemochromatosis (excess iron in the body) or sarcoidosis (inflammation of organs) that could be affecting hormone production.
Step 3 : Are FSH and LH too high?
If the levels of FSH and LH are higher than normal, it suggests that the testicles are not producing enough sperm. This can be caused by various factors such as problems in the testicles themselves, autoimmune diseases, or genetic abnormalities. To investigate further, doctors may recommend tests to examine the genetic makeup of the patient, which can help identify the underlying cause of the infertility.
Step 4 : Are LH and Testosterone Normal?
When evaluating a patient for infertility, it is important to check the levels of certain hormones. In this particular case, the LH (luteinizing hormone) and testosterone levels are normal, indicating that the pituitary gland is functioning properly and the cells responsible for producing testosterone are working. However, the FSH (follicle-stimulating hormone) level is elevated, which could be due to various factors such as unknown causes (idiopathic), genetic factors, or certain medications. Further investigation is recommended to determine the exact cause of the elevated FSH level and the resulting infertility.
Step 5 : Are LH and Testosterone high?
If a patient has a sperm count of 31 and is being evaluated for infertility, it is possible that their LH (luteinizing hormone) and testosterone levels are high. This could indicate a condition called androgenic insensitivity. Androgenic insensitivity means that the body may not respond properly to male hormones, like testosterone, which can affect fertility. Further investigation, such as genetic testing, may be recommended to confirm this condition and understand its impact on fertility.
Is there any treatment for sperm count of 31 million?
Some causes of low sperm count can be treated, others are not totally treatable. Assisted reproductive techniques are required in those cases where the count cannot be improved to normal levels. Here are a few of the treatable and non-treatable causes
Treatable causes of low sperm count
In case of the following causes, treatment can be provided to directly increase the sperm count.
Understanding Obstructive Azoospermia: Low Sperm Count
Obstructive azoospermia is a condition characterized by a low sperm count, where the flow of sperm is blocked due to an obstruction in the reproductive tract.
Understanding Ejaculatory Duct and Prostatic Midline Cysts
Ejaculatory duct and prostatic midline cysts are conditions that can contribute to a low sperm count in men.
Understanding Gonadotropin Deficiency
Gonadotropin deficiency refers to a condition where a man has a low sperm count, which can affect his ability to father a child.
Understanding Low Sperm Count
Low sperm count refers to a condition where a man produces a smaller than normal amount of sperm, which can impact fertility and the ability to conceive.
Understanding Sperm Autoimmunity
Sperm autoimmunity refers to a condition where the body's immune system mistakenly attacks and damages sperm, leading to a low sperm count.
Understanding Varicoceles: Causes and Solutions for Low Sperm Count
Varicoceles are dilated veins in the scrotum that can affect sperm production, leading to low sperm count.
Understanding Reversible Toxin Effects on Low Sperm Count
Reversible toxin effects refer to temporary damage caused by certain substances that can decrease sperm count in men.
Untreatable Causes of low sperm count
In case of these conditions, ART will probably be required as there is no direct treatment to increase the sperm count.
Understanding Primary Seminiferous Tubular Failure
Primary seminiferous tubular failure refers to a condition where a man has a low sperm count, which can affect fertility.
Understanding Sertoli Cell-Only Syndrome: A Low Sperm Count Condition
Sertoli cell-only syndrome is a condition where a person has a low sperm count due to the absence or malfunctioning of certain cells in the testicles.
Understanding Bilateral Orchiectomy
Bilateral orchiectomy, also known as removal of both testicles, is a surgical procedure that may be considered for patients with low sperm count.
Is pregnancy possible with a sperm count of 31 million?
As per
Martorras et al, 7% of men, with a sperm count as low as 2 million/ ml were still able to conceive spontaneoulsy, with natural means, over a 2 year period of trying. This implies that even a low sperm count DOES NOT MEAN that you won't be able to have a successfull pregnancy. There are several other factors at play, and we try to list them out in the rest of the article. Assisted reproductive techniques can greatly increase the chances of conception.
What IVF or assisted conception options are available for a low sperm count?
Intra Uterine Implantation
Intra Uterine Implantation is an assisted reproductive technique that can help couples who are struggling to conceive due to a low sperm count. During this procedure, the doctor will collect sperm from the partner and prepare it in a laboratory. Then, using a tiny tube called a catheter, the prepared sperm is gently placed inside the woman's uterus. This technique increases the chances of sperm reaching the egg and fertilizing it, increasing the chances of pregnancy. It is a safe and minimally invasive procedure that can be done in a doctor's office, offering hope to couples who want to start a family.
Intra Cytoplasmic Sperm
Intra Cytoplasmic Sperm Injection (ICSI) is a special technique used in assisted reproductive technology to help couples who are struggling to conceive due to a low sperm count. During the procedure, a single healthy sperm is directly injected into the woman's egg using a tiny needle. This increases the chances of fertilization as the sperm doesn't have to travel far to reach the egg. Once fertilization occurs, the fertilized egg is then placed in the woman's uterus, where it can hopefully implant and develop into a pregnancy. ICSI has proven to be a successful option for couples facing male infertility issues and can greatly increase their chances of having a baby.
In Vitro Fertilization
In Vitro Fertilization (IVF) is an assisted reproductive technique that can help couples who are struggling to conceive due to low sperm count. During IVF, the eggs from a woman's ovaries are collected and mixed with sperm in a laboratory dish. This allows fertilization to occur outside of the woman's body. Once the eggs are fertilized and embryos are formed, they are then transferred back into the woman's uterus. This increases the chances of successful pregnancy. IVF is a safe and effective option for couples facing infertility issues, helping them fulfill their dream of starting a family.
What is a good plan ART (assisted reproductive technique) plan of action for a sperm count of 31 million?
Based on the patient's sperm concentration of 10.3 million/ml, the recommended first line of treatment would be Intra Uterine Implantation, which is less invasive and cost-effective. This technique has a pregnancy rate of around 16% and has been successful in various studies ranging from 8% to 22%. Intra Cytoplasmic Sperm Injection, the most invasive and costly method, should only be considered if the sperm count is very low (less than 5 million/ml), as it has an efficacy of around 24.2% in such cases. In Vitro Fertilization, the second line of treatment, can be considered if IUI fails after 3-4 cycles. Its success rates range from 7% for counts below 5 million/ml, 10.7% for counts between 5-10 million, and 14.3% for counts above 10 million.
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References
Authorotative articles on IVF and oligospermia
Recommended Tests
The following tests are recommeded as additional investigations in a case of oligospermia or low sperm count.