Book double marker test in Pune at locations near you with Pathofast Lab.Visit our centers or get free home sample collection for the double marker test in Pune.
Double Marker Test in Pregnancy is a blood test done on mothers that checks for abnormal chromosomes in fetus(developing baby). The test should be done between weeks 11-13 of pregnancy. It detects Trisomy 13/18 and Down's Syndrome.
A Double Marker Test in pregnancy is a blood test done on the mother that provides a risk estimate of chromosomal abnormalities in the fetus(developing baby).
This test measures the levels of some hormones in the mother's blood (PAPP-a and free-Beta-HCG), as well as some measurements from a recent USG report, and uses a statistical calculation to predict risk of the fetus having genetic abnormalities. As such the test is predictive and not confirmatory. If a higher than expected risk is predicted, the doctor may go in for additional tests to confirm the findings.
Background: A normal human has 23 pairs of chromosomes. These include 1 pair of sex chromosomes and 22 other pairs. In genetic abnormalities like trisomies - the fetus may have 22 normal pairs of chromosomes, but may have 3 chromosomes instead of 2 at a given position. This gives rise to an uneven number of total chromosomes and can produce abnormalities in the child. These include Down's Syndrome(Trisomy 21), Patau Syndrome(Trisomy 13) and Edwards Syndrome(Trisomy 18)
Double marker test in pregnancy uses statistical models that use levels of hormones in mothers blood to predict the chances of such abnormalities in the fetus.
Which diseases will this test detect: The test predicts chances of Trisomy 13/18, and Trisomy 21 - Down's Syndrome in the fetus. These are called trisomies - because there are 3 chromosomes instead of the normal 2.(due to the presence of 3 chromosomes instead of 2 at any given position)
Why is it important to test for these diseases early?: These disorders are not compatible with a healthy life for the baby. Very often they require intervention on humanitarian grounds. Knowing early on, helps to proceed for confirmatory testing, genetic conselling and intervention if required.
Pathofast Lab in Pune,Camp is centrally located and offers home sample collection services in all parts of Pune City for a variety of lab tests including Double Marker Test.
2nd Floor, Manisha Terrace, 411001, Moledina Rd, Camp, Pune, Maharashtra 411001
You can visit one of our centers. You can walk in at any time to our centers, without the need to book an appointment.
Pathofast Lab was rated as the best diagnostic center in Pune by 5bestInCity and is rated 4.9/5 stars by hundreds of happy patients. We are known for report accuracy, safety and hygiene. Best analyzers ensure highly accurate dual marker test reports
You can get the double marker test with home sample collection at any of our service areas locations, including Jangli Maharaj Nagar, Ravet, Viman Nagar, Shastrinagar, Yerawada, NIBM Undri Road, Kondhwa, Camp, Aundh, Baner, Dattwadi, Undri, Pimpri-Chinchwad, Kalyani Nagar, Koregaon Park, Sadashiv Peth with home sample collection. You need to book an appointment for home sample collection.
Pathofast lab in Pune has trained laboratory technicians, automated analyzers and qualified doctors all of whom function as a team to deliver accurate and timely Double Marker Test reports. The lab is spread over nearly 1500 sq feet, with automated quality control systems that make it an ideal lab for Double Marker test in Pune.
double marker test price is Rs.2900 in Pune. Latest dual marker test price in Pune is Rs.2900 as of 24 January 2024
Home sample collection charges may be applicable depending on your area
Select the nearest location from the dropdown, to estimate the total cost of dual marker test for your area in Pune.
Medicines do not affect the test results.
The Double Marker Test in pregnancy should be done between weeks 11-13 of pregnancy, at any time of the day. It only involves providing a single blood sample.
You do not need to be fasting and there are no food restrictions.
The test needs a recent USG Report (no older than 1 week). This report is generated by means of an Ultrasound Scan / Sonography. You will need to get this sonography done from a nearby qualified radiologist.
The test involves collecting a simple blood sample. There is no special preparation required. The sample can be collected at your home or in the lab center.
The Double Marker Test is intended for pregnant women to assess fetal health.
The test report will list the values of Free Beta-HCG, PPAP-A, Risk of Trisomy 13/18 and Risk of Trisomy 21.
Risk refers to the chance of developing the trisomy(chromosomal abnormality). It is mentioned as 1/(number of normal pregnancies with the same value)
The Double Marker Test can be classified under several categories, including prenatal screening, genetic testing, and risk assessment. Other tests should be done during first trimester screening are listed on our Pregnancy Test in Pune page.
| PAPP-A Pregnancy Protein | Rs. 1500 |
| Beta HCG Test | Rs. 900 |
| Progesterone Test | P4 | Rs. 700 |
| Quadruple Test for Pregnancy | Rs. 3700 |
| Triple Marker Test | Rs. 2900 |
| Normal Ranges for Double Marker Test | |
|---|---|
| Disease Name | Risk Cutoff |
| The normal range for Trisomy 21 (Down's syndrome) | less than 1/250 |
| The normal range for Trisomy 18 | less than 1/100 |
If the Double Marker Test report in pregnancy comes back as screen positive, it is important not to panic
Your doctor will recommend additional tests, such as an amniocentesis or chorionic villus sampling (CVS), to obtain more accurate information.
Risk of Down's Syndrome is considered positive if the chance is more than 1:250 in your case. Down's Syndrome is a genetic disorder caused by the presence of an extra chromosome 21. It leads to developmental delays and physical characteristics such as a flat facial profile and upward-slanting eyes. If a patient is screen positive for Down's Syndrome additional tests like amniocentesis or Chorionic Villus Sampling are done.
Screen positive for Trisomy 18/Trisomy 13 means that there is a chance greater than 1 in 100 that your baby could be carrying these abnormalities. Trisomy 18 is a condition caused by an extra chromosome 18 (Edwards Syndrome), resulting in severe developmental delays, heart defects, and other life-threatening conditions. This condition significantly reduces life expectancy. Trisomy 13 is a genetic disorder is due to an extra chromosome 13, causing severe intellectual disability, physical abnormalities, and often leads to early infant mortality.
When a patient's Double Marker Test report returns abnormal results, it is crucial to consult the right type of medical specialist for further evaluation and management.Typically, the first step is to seek advice from a gynecologist or an obstetrician
| Normal Ranges for Double Marker Test | |
|---|---|
| Disease Name | Risk Cutoff |
| The normal range for Trisomy 21 (Down's syndrome) | less than 1/250 |
| The normal range for Trisomy 18 | less than 1/100 |
Patients are extremely happy with Pathofast Lab for their Double Marker Test, as they trust it for its accurate, reliable, and quick reports.The lab's commitment to maintaining high standards of quality and efficiency has earned it a reputation for excellence in Pune
Whether it's the friendly staff, the state-of-the-art equipment, or the prompt service, Pathofast Lab consistently delivers an exceptional experience for each patient.This unwavering dedication to patient satisfaction makes it the go-to choice for expectant parents looking for trustworthy prenatal screening.
