Triple Marker Test in Pregnancy in Pune Near Me : Price @ Rs 2900 | 2nd Trimester Screen

Last Updated : 19 August 2024 by Dr.Bhargav Raut

Book Triple Marker Test in Pune at locations near you with Pathofast Lab.Visit our centers or get free home sample collection for the Triple Marker Test in Pune.

Triple Marker Test in Pregnancy is a blood test done on mothers that checks for abnormal chromosomes in fetus(developing baby). The test should be done between weeks 15-20 or during the 4th - 5th month of pregnancy. It detects Trisomy 18 and Down's Syndrome and neural tube defects.

The test is also called the 2nd trimester screen, perinatal screening test or Down's Syndrome Screen.

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Triple Marker Test in Pregnancy in Pune Near Me : Price @ Rs 2900

What is 2nd Trimester Screen Test (Triple Marker Test)?

A Triple Marker Test is a blood test done on pregnant women to estimate the risk of their fetus(child) developing chromosomal abnormalities. These include Down's Syndrome, Edwards Syndrome and Neural Tube Defects. The test is not a confirmatory test, but only a risk estimate.

Background: The normal human has 23 pairs of chromosomes. In susceptible mothers, there is a risk of the fetus having 3 chromosomes at certain positions, instead of the usual 2. These include position 18(Edwards Syndrome), position 21(Down's syndrome). Some pregnancies are also complicated when the child develops abnormalities of the spinal chord called neural tube defects. These are often due to vitamin deficiencies.

Why these syndromes must be detected early?: Syndromes like Down's syndrome are not compatible with a healthy life. Early detection is important for intervention if the syndrome can be confirmed.

What is a triple marker test?
  • What is the cost of the Triple Marker Test in Pune?

    Triple Marker Test price in Pune is Rs.2900

  • What type of sample is required for Triple Marker Test

    Triple Marker Test needs a Blood Sample

  • How much time does Triple Marker Test(2nd Trimester Screen) report take?

    Triple Marker Test(2nd Trimester Screen) takes upto 1 days

  • What is the normal range for Triple Marker Test?

    The normal range for Triple Marker Test is < 1:250 for Down's Syndrome, < 1:100 for Trisomy 18 and < 2.05 MOM for Neural Tube Defects.*

  • Is home sample collection available for Triple Marker Test(2nd Trimester Screen) in Pune?

    Yes, home Blood Sample is available for Triple Marker Test(2nd Trimester Screen) in Pune with Pathofast Lab.

  • Is Triple Marker Test report available?

Finding a lab for Triple Marker Test in Pune, near you

Pathofast Lab in Pune,Camp is centrally located and offers home sample collection services in all parts of Pune City for a variety of lab tests including Triple Marker Test.

  • How to find the nearest center for Triple Marker Test in Pune?

    You can visit one of our centers. You can walk in at any time to our centers, without the need to book an appointment.

  • How accurate are Pathofast Lab reports for 2nd Trimester Screen in Pune

    Pathofast Lab was rated as the best diagnostic center in Pune by 5bestInCity and is rated 4.9/5 stars by hundreds of happy patients. We are known for report accuracy, safety and hygiene. Best analyzers ensure highly accurate 2nd Trimester Screen reports

  • How to book appointment for home sample collection for Triple Marker Test in different areas of Pune?

    You can get the Triple Marker Test with home sample collection at any of our service areas locations, including Jangli Maharaj Nagar, Ravet, Viman Nagar, Shastrinagar, Yerawada, NIBM Undri Road, Kondhwa, Camp, Aundh, Baner, Dattwadi, Undri, Pimpri-Chinchwad, Kalyani Nagar, Koregaon Park, Sadashiv Peth with home sample collection. You need to book an appointment for home sample collection.

  • Benefits of getting Triple Marker Test reports with Pathofast Lab?

    Pathofast lab in Pune has trained laboratory technicians, automated analyzers and qualified doctors all of whom function as a team to deliver accurate and timely Triple Marker Test reports. The lab is spread over nearly 1500 sq feet, with automated quality control systems that make it an ideal lab for Triple Marker Test test in Pune.

Triple Marker Test Cost in Pune | Triple Marker Test price near me

Triple Marker Test price near me is Rs.2900 in Pune. Latest 2nd Trimester Screen cost in Pune is Rs.2900 as of 19 August 2024

Home sample collection charges may be applicable depending on your area

Select the nearest location from the dropdown, to estimate the total cost of 2nd Trimester Screen for your area in Pune.

Triple Marker Test Cost in Pune

Requirements for Triple Marker Test(2nd Trimester Screen)

Procedure of triple marker test
  • Which medicines do I have to avoid before this test:

    The Triple Marker Test, also known as the 2nd Trimester Screen, does not require you to stop any specific medicines before taking the test.

  • What is the right time to do this test:

    This screening test is typically performed during the second trimester of pregnancy to assess the risk of Down's Syndrome in the fetus. The blood sample collection can be done at anytime of the day.

  • Do I need to be fasting before this test, and which foods to avoid:

    No fasting is required before taking the Triple Marker Test. You do not need to avoid any specific foods.

  • Any other special instructions for this test:

    A recent USG report is necessary for the statistical calculations performed in the test.

Procedure of Triple Marker Test

The 2nd Trimester Screen, also known as the Triple Marker Test, is conducted by collecting a blood sample from the patient

How is the sample collected for Triple Marker Test?

  • Visit lab or request home sample collection: Visit one of our centers near you in Pune, or book a home sample collection. You can do this by calling the lab or through our online booking platform. Make sure that you have a recent USG report with you at the time of visiting the lab
  • Sit comfortably so that your arm is visible: The lab technician will request you to sit comfortably so that your arm is visible
  • Sample is collected using needle: A needle is inserted into your vein and a few tubes of blood are collected.

How to book an appointment for Triple Marker Test in Pune at Pathofast Lab?

  • Call the lab: Call the lab on our mobile number : 8956690418, or our landline 02049304930, and ask the reception to book an appointment for you.
  • Book on Watsapp: Click here to book the Triple Marker Test through watsapp using our simple and friendly chatbot.
  • Book Online: Click here to book the Triple Marker Test online, with instant confirmation.

Who should do the Triple Marker Test?

The Triple Marker Test is intended for pregnant women in their second trimester.

List of symptoms that may mean you need a Triple Marker Test?

  • Advanced Maternal Age:Women above the age of 35 are at a higher risk of bearing fetuses with chromosomal abnormalities.
  • Family History:: A family history of genetic disorders or chromosomal abnormalities necessitates a Triple Marker Test to rule out potential issues.
  • Abnormal Ultrasound Findings:: If an ultrasound shows markers for potential abnormalities, a Triple Marker Test can provide further insight.
  • Previous Pregnancy Complications:: Women who have experienced complications in prior pregnancies may benefit from a Triple Marker Test to ensure a healthy pregnancy.
  • IVF Pregnancies:: Pregnancies achieved through In-Vitro Fertilization (IVF) are at a slightly higher risk of chromosomal anomalies, warranting a 2nd trimester screen.
  • Unexplained Miscarriages:: Multiple unexplained miscarriages can be a sign of underlying chromosomal issues, making a Triple Marker Test advisable.

Eligibility Criteria for Triple Marker Test

  • Women in 2nd trimester of pregnancy:The 2nd Trimester Screen is typically performed during the 15th to 20th weeks of pregnancy.
  • Medical History::Women with a family history of genetic disorders or previous pregnancies with chromosomal abnormalities may be advised to take the test.

What will be included in the Triple Marker Test report?

The triple marker test report includes the values of 3 measured hormones, as well as the risk of Trisomy 21, Trisomy 18 and Neural Tube Defects. The report also includes some other parameters like the weight, the date of the last menstrual period and ethnicity.

What is included in triple marker test report?

List of items included in the Triple Marker Test report | Triple Marker Test

  • Beta-HCG:Beta-HCG level is increased during pregnancy and is one of the factors used to measure the risk of trisomies.
  • Alpha Feto Protein:AFP or Alpha feto protein is a protein that has a wide variety of uses. It is a part of the triple marker test report. In non-pregnant women it is used to assess the risk of liver cancers.
  • Free E3-Free Estriol::Free Estriol is the free or unbound portion of the estrogen. This is also measured during the triple marker test.
  • LMP::The Last Menstrual Period date helps in determining the gestational age of the fetus.
  • Date of Birth::The mother's date of birth is used to calculate age-related risks associated with pregnancy.
  • Weight::The mother's weight is considered to adjust the levels of various markers for accurate risk assessment.
  • Week of Pregnancy::Knowing the exact week of pregnancy is crucial for interpreting test results correctly.
  • Ethnic Origin::Ethnic background can influence the levels of certain markers and is important for accurate risk calculation.
  • Trisomy 18 Risk::This parameter indicates the probability of the fetus having Edwards syndrome. The normal range is less than 1%
  • Trisomy 21 Risk::This parameter shows the likelihood of the fetus having Down syndrome. The normal range is less than 0.25%
  • Neural tube defects risk::This assesses the risk of defects in the brain, spine, or spinal cord, such as spina bifida. The normal range is < 2.05 MOM (Alpha feto protein)

Which other tests can I do together with Triple Marker Test?

The triple marker test is to be done in the 2nd trimester of pregnancy and is a part of the various perinatal screening tests. During this trimester certain other tests before pregnany also must be done. You can get a complete list of tests to be done before pregnancy.

Frequently Asked Questions about Triple Marker Test

A double marker test is a test done in the first trimester of pregnancy, and measures two hormones namely PAPP-A and free-beta-hcg. The triple marker test is done in the second trimester of pregnancy and includes three parameters - alpha feto protein, beta-hcg and Free Estradiol. Both tests screen for Down's syndrome. The triple marker test additionally screens for neural tube defects. The double marker test screens for Trisomy 13 (Edwards Syndrome). The triple marker test is more sensitive and accurate than the double marker test.

The triple marker test is usually done in the 4th or 5th month of pregnancy

Triple marker test is done in weeks 15-20 of pregnancy.

A positive triple marker test is when the risk of Trisomy 21(Downs Syndrome) is more than 1/260, or the risk of neural tube defects is more than 2.05 MOM, or the risk of Trisomy 18 is more than 1/100. A positive triple marker test requires further investigation by means of amniocentesis or chorionic villus sampling - discussed in report interpretation section.

The quadruple marker test is more sensitive and accurate than the triple marker test. This is because it uses additional parameters for risk estimation.

The following diseases may be related to abnormal results in the Triple Marker Test : Trisomy 21 (Downs Syndrome), Trisomy 18 (Edwards Syndrome), Trisomy 13 (Patau Syndrome), Neural tube defects, Chromosomal abnormalities, Multiple pregnancies, Hypothyroidism, Anemia, Rh incompatibility, Infectious diseases

If you have any of these symptoms you should consider getting a Triple Marker Test test : Frequent Urination

No, Pathofast is a diagnostic laboratory and we do not offer consultations. If you have questions about the report/results, our pathologist will definitely discuss them with you.

If you book a home sample collection, the payment must be made at the time of the booking. If you visit the lab, the payment must be made at the time of giving your sample. We do not accept samples for processing without advance payment.

Each report contains a QR code. The QR code if scanned by any QR code application will load our website and prove to your insurance company that the report was indeed done at our lab.

You can pay by cash, card, online using Gpay, or any other UPI app.

You can book the report online

You will receive the reports by watsapp and email as a pdf.

To get the hard copy of the reports you will have to visit the lab.

The Triple Marker Test test report is usually ready in 1 days

Yes home visit for sample collection is available in most suburbs of Pune

We offer free home sample collection at any location within 1 km of the lab processing center. For areas outside 15km, please choose your suburb to check the approximate visit charges.

Prenatal screening is an essential component of prenatal care, encompassing a series of tests and procedures conducted during both the first and second trimesters of pregnancy to assess the health of the expectant mother and the developing fetus.. n the first trimester, common tests include the nuchal translucency ultrasound, which measures the fluid at the back of the baby's neck, and the blood test that analyzes pregnancy-associated plasma protein-A (PAPP-A) and human chorionic gonadotropin (hCG) levels. These tests aim to screen for chromosomal abnormalities such as Down syndrome and trisomy 18.. Moving into the second trimester, prenatal screening involves the Triple Marker Test, which examines maternal blood for alpha-fetoprotein (AFP), hCG, and unconjugated estriol levels. Additionally, an ultrasound known as the anatomy scan or anomaly scan is performed to evaluate the baby's physical development and screen for structural abnormalities.

The Triple Marker Test, also known as the Triple Test or the Multiple Marker Screening, is a prenatal screening procedure that aims to assess the risk of specific fetal abnormalities.. Down Syndrome: This genetic condition is caused by an extra copy of chromosome 21, resulting in intellectual disabilities, distinct facial features, and potential health complications. The Triple Marker Test measures levels of alpha-fetoprotein (AFP), human chorionic gonadotropin (hCG), and unconjugated estriol (uE3) in the mother's blood to help identify pregnancies at increased risk of Down syndrome.. Trisomy 18 (Edwards Syndrome): Trisomy 18 is a chromosomal disorder characterized by the presence of an extra copy of chromosome 18. Babies with this condition often have severe developmental delays, heart defects, and other organ abnormalities. The Triple Marker Test can help detect pregnancies with an elevated risk of Trisomy 18 by assessing the levels of AFP, hCG, and uE3 in the maternal blood.. The Triple marker test only provides an estimation of the risk of these diseases. Further investigation is needed if the risk score is high. The test is not confirmatory.

The right timing or period for the triple marker test is the second trimester.. The second trimester starts at the beginning of the 4th month of the pregnancy, and ends at the end of the 6th month of gestation.. Triple marker test is usually recommended between 15-20 weeks of gestation.

Normal Range for Triple Marker Test

Triple Marker Test Normal Range

Triple Marker Test normal range in women

Normal Ranges for Triple Marker Test
Disease Name Risk Cutoff
The normal range for Trisomy 21 (Down's syndrome) less than 1/250
The normal range for Trisomy 18 less than 1/100
The normal range for Neural Tube Defects less than 2.05 MOM

What to do if Triple Marker Test report is abnormal?

A positive triple marker test report, means that there is increased risk of trisomies or neural tube defects. In such a case, you will need to go in for additional testing like amniocentesis or chorionic villus sampling.

What is Down's Syndrome?

List of common abnormalities in the Triple Marker Test report

  • Down Syndrome:

    This is a genetic disorder caused by the presence of an extra chromosome 21. The 2nd Trimester Screen can help detect this condition, which is associated with intellectual disability and physical abnormalities.

  • Edward’s Syndrome:

    Also known as Trisomy 18, Edward’s Syndrome is a severe genetic disorder characterized by the presence of an extra chromosome 18. It results in serious developmental and physical issues.

  • Neural Tube Defects:

    These defects are related to the brain and spinal cord, such as spina bifida and anencephaly. The 2nd Trimester Screen can indicate the likelihood of these severe conditions.

Which type of doctor do I have to consult to understand my report?

Consult your obstetrician for further guidance.

Treatment and Interpretation

What are Neural Tube Defects?

Interpretation

What are the normal values for AFP, Uconjugated Estriol and Beta Hcg for different weeks of gestation?

Weeks of Gestation AFP Levels Uconjugated Estriol Values Beta HCG Values
14 25.5 3.44 18.1
15 27.7 4.11 15.2
16 30.9 4.95 12.1
17 34.6 5.87 10.2
18 38.55 6.67 8.45
19 42.7 7.63 7.39
.

References
: Kaur G, Srivastav J, Sharma S, Huria A, Goel P, Chavan BS

Maternal serum median levels of alpha-foetoprotein, human chorionic gonadotropin & unconjugated estriol in second trimester in pregnant women from north-west India.Indian J Med Res

2013;138(1):83-8.PMID: 24056560; PMCID: PMC3767258.

What are the normal risk evaluation cut-offs for detecting different diseases based on the results of the Triple Marker Test

The normal risk cutoffs for various genetic disorders based on the Triple Marker Test are as follows:

Condition Risk
Downs Syndrome 1:270
Edwards Syndrome 1:350
Neural Tube Defects AFP > 2.5 MoM
.Reference: Chen, Y., Wang, X., Li, L

et al.New cut-off values for screening of trisomy 21, 18 and open neural tube defects (ONTD) during the second trimester in pregnant women with advanced maternal age

BMC Pregnancy Childbirth 20, 776 (2020).https://doi.org/10.1186/s12884-020-03464-z

Patient Reviews

Patients are extremely satisfied with Pathofast Lab for the Triple Marker Test, also known as the 2nd Trimester Screen.They trust the lab for its accurate, reliable, and quick reports

The dedication to precision and speed has made Pathofast Lab a preferred choice for expecting parents seeking the Triple Marker Test.The lab's commitment to high standards ensures that every result is dependable, giving patients peace of mind during their pregnancy journey.

  • Prompt Results(5/5)

    Received my Triple Marker Test report within hours in Kothrud.- Manisha K.

  • Hygienic and Reliable(5/5)

    Clean lab with trustworthy results for my Triple Marker Test in Hadapsar.- Sneha R.

  • Efficient Service(5/5)

    Quick and efficient Triple Marker Test service in Baner.- Priya S.

  • Professional Staff(5/5)

    The staff was very professional, and my Triple Marker Test was done smoothly in Viman Nagar.- Anjali T.

  • Highly Recommend(5/5)

    Highly recommend for Triple Marker Test, very clean and fast service in Aundh.- Sarika M.

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