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Overview

ANA Blot 17 antigens is a laboratory test used to detect autoantibodies in the blood of patients suspected of having an autoimmune disease. The test is performed by exposing the patients serum to a panel of 17 antigens and detecting the presence of autoantibodies using a technique called immunoblotting. The test can provide information on the specific autoantibodies present in the patients blood, which can help in the diagnosis and management of autoimmune diseases such as lupus or rheumatoid arthritis.

Who should do this test?

Patients with suspected autoimmune diseases: ANA Blot 17 antigens test is commonly used as a diagnostic tool for autoimmune diseases such as systemic lupus erythematosus, Sjogrens syndrome, and rheumatoid arthritis.

Patients with unexplained symptoms: ANA Blot 17 antigens test may be ordered if a patient is experiencing unexplained symptoms such as joint pain, fatigue, and fever, and other diagnostic tests have not been conclusive.

Patients with a family history of autoimmune diseases: Patients with a family history of autoimmune diseases may undergo ANA Blot 17 antigens test as a preventive measure to detect the early signs of autoimmune diseases.

What to do if the test is abnormal?

The first step would be to consult a healthcare provider who is experienced in interpreting ANA results. ANA Blot 17 is a type of test that looks for antibodies in the blood that are associated with autoimmune diseases such as lupus, rheumatoid arthritis, and Sjogrens syndrome.

If the ANA Blot 17 results are abnormal, it does not necessarily mean that the person has an autoimmune disease. Further testing, including a physical exam, medical history, and additional blood tests, may be necessary to confirm or rule out a diagnosis.

In the meantime, the person should continue to monitor their symptoms and report any changes or new symptoms to their healthcare provider. Depending on the situation, treatment may be necessary to manage symptoms and prevent complications.

What is the normal range of ANA Blot Assay / ENA (17 Antigens) (including Ku and Mi)?

The normal range for adult males is 0.0-5.0,the normal range for adult females is 0.0-5.0

Frequently Asked Questions

The ANABlot panel covers the major antigens associated with the most common autoimmune disorders. The following table lists the antigens.. Antigens RNP/Sm (RNP/Sm) Sm (Sm) SS-A native (60 kDa) (SSA) Ro-52 recombinant (52) SS-B (SSB) Scl-70 (Scl) PM-Scl100 (PM100) Jo-1 (Jo) Centromere B (CB) PCNA (PCNA) dsDNA (DNA) Nucleosomes (NUC) Histones (HI) Ribosomal-P-protein (RIB) AMA-M2 (M2) Mi-2 Ku

Several autoimmune diseases show positivity to these antigens. Here is a table describing common autoimmune diseases and how they manifest in the human body. Disease Description Systemic lupus erythematosus (SLE)An autoimmune disease characterized by inflammation and damage to various tissues in the body. MCTD (Sharp syndrome)A mixed connective tissue disease involving symptoms of lupus, scleroderma, and polymyositis. Systemic SclerosisAn autoimmune disorder causing fibrosis and thickening of the skin and other connective tissues. PolydermatomyositisAn inflammatory disease affecting the skin and muscles, causing weakness and skin rash. Sjogren syndromeAn autoimmune disorder primarily affecting the salivary and tear glands, leading to dry mouth and eyes. Neonatal lupus erythematosusAn uncommon condition where a newborn develops lupus-related skin rashes due to maternal autoantibodies. Progressive systemic sclerosisAlso known as systemic scleroderma, it involves thickening and scarring of the skin and internal organs. PolymyositisAn inflammatory disease causing muscle weakness and inflammation in the muscles. DermatomyositisAn inflammatory disorder affecting the muscles and skin, leading to muscle weakness and skin rash. Primary biliary cirrhosisAn autoimmune disease affecting the liver's small bile ducts, leading to liver damage and cirrhosis. Drug induced lupusA lupus-like syndrome triggered by certain medications, causing symptoms similar to SLE. Rheumatoid arthritisAn autoimmune disorder primarily affecting the joints, causing pain, swelling, and joint damage.

Why Choose Pathofast for ANA Blot 17 antigens

Pathofast Lab in Pune, is the best lab in Pune for accurate and reliable blood tests. Our lab is located conveniently in the center of Pune and we also offer home sample collection for the ANA Blot 17 antigens in various areas of Pune.

You can be assured of quality service and timely and accurate reports

Home Sample Collection is Available for ANA Blot 17 antigens at the following locations in Pune :

  • Jangli Maharaj Nagar
  • Ravet
  • Viman Nagar
  • Shastrinagar, Yerawada
  • NIBM Undri Road, Kondhwa
  • Camp
  • Aundh
  • Baner
  • Dattwadi
  • Undri
  • Pimpri-Chinchwad
  • Kalyani Nagar
  • Koregaon Park
  • Sadashiv Peth