The Direct Coombs test, also known as Direct Antiglobulin Test (DAT), is a laboratory test used to detect antibodies that attach to red blood cells (RBCs). It is performed by mixing patients RBCs with a special antibody that can detect and bind to antibodies on the surface of RBCs. If the test is positive, it indicates the presence of antibodies that are coating the RBCs and causing them to be destroyed by the immune system.
Patients with suspected autoimmune hemolytic anemia: Direct Coombs Test is primarily used to diagnose autoimmune hemolytic anemia, a condition in which the bodys immune system attacks its own red blood cells. This test helps to detect the presence of antibodies on the surface of red blood cells.
Newborns with jaundice: Direct Coombs Test is also performed on newborns with jaundice to determine if there is an underlying hemolytic disease of the newborn. In this condition, antibodies from the mothers blood cross the placenta and attack the babys red blood cells.
Patients with a history of blood transfusions: Direct Coombs Test is sometimes performed on patients who have received blood transfusions to determine if there is a reaction between the patients antibodies and the donors red blood cells. This is important to prevent transfusion reactions in the future.
Follow up with your physician: If the results of your Direct Coombs test are abnormal, it is important to follow up with your physician. Your physician will be able to provide you with a thorough explanation of what the results mean, and what steps should be taken next.
Additional testing: Your physician may suggest additional testing to determine the underlying cause of the abnormal results. This may include further blood tests or imaging studies.
Treatment: Treatment for an abnormal Direct Coombs test will depend on the underlying cause. Your physician will be able to recommend appropriate treatment options and work with you to develop a treatment plan.
Pathofast Lab in Pune, is the best lab in Pune for accurate and reliable blood tests. Our lab is located conveniently in the center of Pune and we also offer home sample collection for the Direct Coomb's Test in various areas of Pune.
You can be assured of quality service and timely and accurate reports