Creatinine 4.9 mg/dl means : causes, treatment, GFR calculation
In this article we discuss what a creatinine value of 4.9 mg /dl means, what are its causes and how to calculate your estimated Glomerular Filtration Rate based on the GFR, as well its implications on your kidney health. We also answer the question about whether a Creatinine level of 4.9 is dangerous, good or bad.Published Date : 2023-07-08T00:31:57.337Z
Updated Date : 2024-04-11T19:29:33.116+05:30
Table of Contents
What is Creatinine?
How is creatinine measured?
What does a creatinine of 4.9 mg/dl mean in men?
What does a creatinine of 4.9 mg/dl mean in women?
Is creatinine 4.9 dangerous?
What is the normal range and is a creatinine of 4.9 mg/dl normal?
What could cause a creatinine level of 4.9?
What other tests should be done if creatinine level is 4.9?
What is the relation between creatinine and kidney function?
Why do doctors ask for GFR if my creatinine level is 4.9?
What is my GFR if my creatinine level is 4.9?
References
Recommended Tests
What is Creatinine?
Serum creatinine is a substance that our bodies naturally produce as a result of a chemical called creatine phosphate found in our muscles. It is made in a steady and consistent manner. The amount of serum creatinine in our blood depends on how much muscle we have – so men typically have more than women. Interestingly, during pregnancy, the levels of serum creatinine tend to be lower. Essentially, serum creatinine serves as a helpful indicator of muscle mass and can vary based on factors like gender and pregnancy.1
How is creatinine measured?
Before undergoing a serum creatinine lab test, it's important to follow certain pretest preparations. This may include abstaining from eating or drinking anything, apart from water, for a specific period of time. Once you arrive at the lab, a healthcare professional will collect a small sample of your blood using a needle. This blood sample will then be sent to the lab, where they will measure the concentration of creatinine present in your blood. This test helps to assess kidney function and identify any potential kidney problems.
What does a creatinine of 4.9 mg/dl mean in men?
A normal creatinine level for women is between 0.73 and 1.18. If your creatinine level is 4.9 mg/dl, it is very dangerous for your health. It is strongly recommended that you go to the hospital right away. You may need dialysis treatment. Please do not try to treat yourself without medical help.3,4
What does a creatinine of 4.9 mg/dl mean in women?
A normal creatinine level for women is between 0.55 and 1.02. Having a creatinine value of 4.9 mg/dl is very dangerous. It is important to go to the hospital right away for treatment, which may include dialysis. Do not try to treat yourself without medical help.3,4
Is creatinine 4.9 dangerous?
A creatinine of may be dangerous depending on your gender and age. The tables below highlight the likelihood of a creatinine of being dangerous for different age groups in both men and women. We provide the following tables, based on the estimated GFR corresponding to the value of creatinine.
Table of danger posed by Creatinine 4.9 in male across different ages
| Age Group | Is Creatinne of 4.9 dangerous? |
|---|---|
| 25yrs - 95 yrs | very dangerous, Get immediate medical advice and treatment. |
Table of danger posed by Creatinine 4.9 in female across different ages
| Age Group | Is Creatinne of 4.9 dangerous? |
|---|---|
| 25yrs - 95 yrs | very dangerous, Get immediate medical advice and treatment. |
What is the normal range and is a creatinine of 4.9 mg/dl normal?
The normal range for creatinine in men is 0.73 to 1.18 mg/dl, and in women it is 0.55 to 1.02 mg/dl2. Based on these ranges, a creatinine level of 4.9 is considered abnormal.
What could cause a creatinine level of 4.9?
- Acute kidney injury: Sudden loss of kidney function, often caused by dehydration, sudden drop in blood flow to the kidneys, or certain medications.
- Chronic kidney disease: Long-term damage to the kidneys, usually caused by conditions like diabetes or high blood pressure.
- Urinary tract obstruction: Blockage in the urinary tract, which can prevent the normal flow of urine and lead to kidney damage.
- Kidney infection: Infection that affects the kidneys, often resulting from a urinary tract infection that spreads upwards.
- Glomerulonephritis: Inflammation of the tiny filters in the kidneys, which can impair their function.
- Nephrotic syndrome: Condition characterized by excessive protein loss in the urine, leading to kidney damage.
- Polycystic kidney disease: Inherited disorder causing the growth of numerous cysts in the kidneys, leading to their progressive enlargement and dysfunction.
- Interstitial nephritis: Inflammation of the kidney's tubules and surrounding structures, often caused by medications or autoimmune diseases.
- Renal artery stenosis: Narrowing of the arteries that supply blood to the kidneys, which can reduce their function.
- Amyloidosis: Condition in which abnormal protein deposits (amyloid) build up in the kidneys, interfering with their normal functioning.
What other tests should be done if creatinine level is 4.9?
Serum Electrolytes
The Serum Electrolytes test is important in this case as it helps to evaluate the balance of electrolytes in the body, including sodium, potassium, chloride, and bicarbonate. Abnormal levels of these electrolytes can indicate kidney dysfunction, which may be the underlying cause of the high creatinine level. Monitoring electrolyte levels can guide treatment and help prevent complications associated with kidney dysfunction.
Blood Urea
The Blood Urea test is important because it measures the amount of urea nitrogen in the blood, which is a waste product formed from the breakdown of protein. A high level of urea indicates impaired kidney function, which can be indicated by a high creatinine level. Therefore, the Blood Urea test helps to assess kidney function and diagnose conditions such as kidney disease.
Estimated GFR
The Estimated GFR (glomerular filtration rate) test is crucial in assessing kidney function because it provides an estimate of how well the kidneys are filtering waste products from the blood. A creatinine level of 4.9 mg/dl indicates impaired kidney function, but the Estimated GFR test can give a more accurate representation of the extent of the impairment and help guide treatment decisions. It is a key tool in diagnosing and monitoring chronic kidney disease.
HBA1C
The HbA1c test is important in this case as it helps determine long-term blood sugar control, as opposed to a single measurement from a fasting blood glucose test. Since chronically elevated blood sugar levels can contribute to kidney damage, the HbA1c test can provide valuable information on the patient's risk for kidney complications. Additionally, it can help guide treatment decisions and monitor the effectiveness of interventions aimed at managing diabetes and reducing the risk of further kidney damage.
LDH
The LDH (lactate dehydrogenase) test is important in this case because it helps evaluate kidney function. A high creatinine level indicates impaired kidney function, and LDH can assist in determining the cause, such as kidney damage or disease. Additionally, LDH levels can also indicate tissue damage in other organs, helping to identify any potential underlying conditions.
Random Sugar
The Random Sugar test is important because it can help determine if the high creatinine level is due to uncontrolled diabetes. High blood sugar levels can damage the kidneys and cause an increase in creatinine levels. Identifying and managing diabetes is crucial in order to prevent further kidney damage and complications.
What is the relation between creatinine and kidney function?
Creatinine, a chemical synthesized within the body at a consistent pace, is entirely eliminated in the urine through the filtration process of the kidney. In the event of any impairment to kidney functionality, creatinine levels experience an upward surge. Hence, creatinine serves as an extremely valuable means to assess the efficiency of renal performance.
Why do doctors ask for GFR if my creatinine level is 4.9?
Glomerular Filtration Rate or GFR is the rate at which a given volume of blood is cleared of any substance every unit of time. This basically is a measure of the filtration capacity of the kidney. Even a small reduction in GFR can have consequences in patients who already have comorbidities. The GFR is calculated from the level of creatinine in the blood using a variety of equations like the MDRD equation given as follows : GFR (mL/min/1.73 m2) = 175 × (Scr)-1.154 × (Age)-0.203 × (0.742 if female) × (1.212 if African American). Using this formula the value of GFR can be calculated just by knowing the level of creatinine in the blood.
What is my GFR if my creatinine level is 4.9?
Estimated Glomerular Filtration Rate (GFR) for a creatinine value of 4.9
| Age in Years | Estimated Glomerular Filtration Rate (GFR) | GFR Grade |
|---|---|---|
| 18 yrs | Male : 15.55 mL/min/1.73 m2 Female : 11.54 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 19 yrs | Male : 15.38 mL/min/1.73 m2 Female : 11.41 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 20 yrs | Male : 15.22 mL/min/1.73 m2 Female : 11.29 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 21 yrs | Male : 15.07 mL/min/1.73 m2 Female : 11.18 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 22 yrs | Male : 14.93 mL/min/1.73 m2 Female : 11.08 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 23 yrs | Male : 14.8 mL/min/1.73 m2 Female : 10.98 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 24 yrs | Male : 14.67 mL/min/1.73 m2 Female : 10.88 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 25 yrs | Male : 14.55 mL/min/1.73 m2 Female : 10.79 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 26 yrs | Male : 14.43 mL/min/1.73 m2 Female : 10.71 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 27 yrs | Male : 14.32 mL/min/1.73 m2 Female : 10.63 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 28 yrs | Male : 14.22 mL/min/1.73 m2 Female : 10.55 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 29 yrs | Male : 14.12 mL/min/1.73 m2 Female : 10.47 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 30 yrs | Male : 14.02 mL/min/1.73 m2 Female : 10.4 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 31 yrs | Male : 13.93 mL/min/1.73 m2 Female : 10.33 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 32 yrs | Male : 13.84 mL/min/1.73 m2 Female : 10.27 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 33 yrs | Male : 13.75 mL/min/1.73 m2 Female : 10.2 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 34 yrs | Male : 13.67 mL/min/1.73 m2 Female : 10.14 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 35 yrs | Male : 13.59 mL/min/1.73 m2 Female : 10.08 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 36 yrs | Male : 13.51 mL/min/1.73 m2 Female : 10.02 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 37 yrs | Male : 13.43 mL/min/1.73 m2 Female : 9.97 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 38 yrs | Male : 13.36 mL/min/1.73 m2 Female : 9.91 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 39 yrs | Male : 13.29 mL/min/1.73 m2 Female : 9.86 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 40 yrs | Male : 13.22 mL/min/1.73 m2 Female : 9.81 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 41 yrs | Male : 13.16 mL/min/1.73 m2 Female : 9.76 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 42 yrs | Male : 13.09 mL/min/1.73 m2 Female : 9.71 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 43 yrs | Male : 13.03 mL/min/1.73 m2 Female : 9.67 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 44 yrs | Male : 12.97 mL/min/1.73 m2 Female : 9.62 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 45 yrs | Male : 12.91 mL/min/1.73 m2 Female : 9.58 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 46 yrs | Male : 12.85 mL/min/1.73 m2 Female : 9.54 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 47 yrs | Male : 12.8 mL/min/1.73 m2 Female : 9.5 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 48 yrs | Male : 12.74 mL/min/1.73 m2 Female : 9.46 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 49 yrs | Male : 12.69 mL/min/1.73 m2 Female : 9.42 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 50 yrs | Male : 12.64 mL/min/1.73 m2 Female : 9.38 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 51 yrs | Male : 12.59 mL/min/1.73 m2 Female : 9.34 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 52 yrs | Male : 12.54 mL/min/1.73 m2 Female : 9.3 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 53 yrs | Male : 12.49 mL/min/1.73 m2 Female : 9.27 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 54 yrs | Male : 12.44 mL/min/1.73 m2 Female : 9.23 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 55 yrs | Male : 12.4 mL/min/1.73 m2 Female : 9.2 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 56 yrs | Male : 12.35 mL/min/1.73 m2 Female : 9.16 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 57 yrs | Male : 12.31 mL/min/1.73 m2 Female : 9.13 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 58 yrs | Male : 12.26 mL/min/1.73 m2 Female : 9.1 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 59 yrs | Male : 12.22 mL/min/1.73 m2 Female : 9.07 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 60 yrs | Male : 12.18 mL/min/1.73 m2 Female : 9.04 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 61 yrs | Male : 12.14 mL/min/1.73 m2 Female : 9.01 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 62 yrs | Male : 12.1 mL/min/1.73 m2 Female : 8.98 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 63 yrs | Male : 12.06 mL/min/1.73 m2 Female : 8.95 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 64 yrs | Male : 12.02 mL/min/1.73 m2 Female : 8.92 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 65 yrs | Male : 11.98 mL/min/1.73 m2 Female : 8.89 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 66 yrs | Male : 11.94 mL/min/1.73 m2 Female : 8.86 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 67 yrs | Male : 11.91 mL/min/1.73 m2 Female : 8.84 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 68 yrs | Male : 11.87 mL/min/1.73 m2 Female : 8.81 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 69 yrs | Male : 11.84 mL/min/1.73 m2 Female : 8.78 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 70 yrs | Male : 11.8 mL/min/1.73 m2 Female : 8.76 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 71 yrs | Male : 11.77 mL/min/1.73 m2 Female : 8.73 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 72 yrs | Male : 11.74 mL/min/1.73 m2 Female : 8.71 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 73 yrs | Male : 11.7 mL/min/1.73 m2 Female : 8.68 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 74 yrs | Male : 11.67 mL/min/1.73 m2 Female : 8.66 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 75 yrs | Male : 11.64 mL/min/1.73 m2 Female : 8.64 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 76 yrs | Male : 11.61 mL/min/1.73 m2 Female : 8.61 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 77 yrs | Male : 11.58 mL/min/1.73 m2 Female : 8.59 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 78 yrs | Male : 11.55 mL/min/1.73 m2 Female : 8.57 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 79 yrs | Male : 11.52 mL/min/1.73 m2 Female : 8.55 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 80 yrs | Male : 11.49 mL/min/1.73 m2 Female : 8.52 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 81 yrs | Male : 11.46 mL/min/1.73 m2 Female : 8.5 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 82 yrs | Male : 11.43 mL/min/1.73 m2 Female : 8.48 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 83 yrs | Male : 11.4 mL/min/1.73 m2 Female : 8.46 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 84 yrs | Male : 11.37 mL/min/1.73 m2 Female : 8.44 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 85 yrs | Male : 11.35 mL/min/1.73 m2 Female : 8.42 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 86 yrs | Male : 11.32 mL/min/1.73 m2 Female : 8.4 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 87 yrs | Male : 11.29 mL/min/1.73 m2 Female : 8.38 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 88 yrs | Male : 11.27 mL/min/1.73 m2 Female : 8.36 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 89 yrs | Male : 11.24 mL/min/1.73 m2 Female : 8.34 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 90 yrs | Male : 11.22 mL/min/1.73 m2 Female : 8.32 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 91 yrs | Male : 11.19 mL/min/1.73 m2 Female : 8.3 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 92 yrs | Male : 11.17 mL/min/1.73 m2 Female : 8.29 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 93 yrs | Male : 11.14 mL/min/1.73 m2 Female : 8.27 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 94 yrs | Male : 11.12 mL/min/1.73 m2 Female : 8.25 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 95 yrs | Male : 11.09 mL/min/1.73 m2 Female : 8.23 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
References
Authorotative articles on serum creatinine
Recommended Tests
The following tests are recommeded as additional investigations for a creatinine of 4.9
HBA1C
Visit HBA1C Test to know more
Electrolytes
Visit Electrolytes to know more
Kidney Profile
Visit Kidney Profile to know more
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Dr.Bhargav Raut is a qualified Pathologist, with over 5 years of experience in the field
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