Creatinine 7.5 mg/dl means : causes, treatment, GFR calculation
In this article we discuss what a creatinine value of 7.5 mg /dl means, what are its causes and how to calculate your estimated Glomerular Filtration Rate based on the GFR, as well its implications on your kidney health. We also answer the question about whether a Creatinine level of 7.5 is dangerous, good or bad.Published Date : 2023-07-13T00:31:57.337Z
Updated Date : 2024-04-11T19:29:33.963+05:30
Table of Contents
What is Creatinine?
How is creatinine measured?
What does a creatinine of 7.5 mg/dl mean in men?
What does a creatinine of 7.5 mg/dl mean in women?
Is creatinine 7.5 dangerous?
What is the normal range and is a creatinine of 7.5 mg/dl normal?
What could cause a creatinine level of 7.5?
What other tests should be done if creatinine level is 7.5?
What is the relation between creatinine and kidney function?
Why do doctors ask for GFR if my creatinine level is 7.5?
What is my GFR if my creatinine level is 7.5?
References
Recommended Tests
What is Creatinine?
Serum creatinine is a substance that our bodies make as a result of a chemical called creatine phosphate, which is found in our muscles. It's like a leftover product that our body produces at a steady pace. The amount of serum creatinine we have in our blood is influenced by how much muscle we have – so generally, men tend to have more than women. However, during pregnancy, the levels of serum creatinine are usually lower. So, in simple terms, serum creatinine is a natural byproduct in our blood that tells us about our muscle mass and can vary depending on our gender and whether or not we're expecting a baby.1
How is creatinine measured?
A serum creatinine lab test is a simple blood test that helps doctors understand how well our kidneys are functioning. Before the test, it's important to inform the doctor about any medications or supplements we are taking, as some might affect the results. On the day of the test, a healthcare professional will draw a small amount of blood from our arm using a needle. This blood sample is then sent to the lab, where they measure the concentration of creatinine, a waste product produced by our muscles. By analyzing the creatinine level, doctors can evaluate the health of our kidneys and identify any potential issues.
Is creatinine 7.5 dangerous?
A creatinine of may be dangerous depending on your gender and age. The tables below highlight the likelihood of a creatinine of being dangerous for different age groups in both men and women. We provide the following tables, based on the estimated GFR corresponding to the value of creatinine.
Table of danger posed by Creatinine 7.5 in male across different ages
| Age Group | Is Creatinne of 7.5 dangerous? |
|---|---|
| 25yrs - 95 yrs | very dangerous, Get immediate medical advice and treatment. |
Table of danger posed by Creatinine 7.5 in female across different ages
| Age Group | Is Creatinne of 7.5 dangerous? |
|---|---|
| 25yrs - 95 yrs | very dangerous, Get immediate medical advice and treatment. |
What is the normal range and is a creatinine of 7.5 mg/dl normal?
The normal range for creatinine in men is 0.73 to 1.18 mg/dl, and in women it is 0.55 to 1.02 mg/dl2. Based on these ranges, a creatinine level of 7.5 is considered abnormal.
What could cause a creatinine level of 7.5?
- Acute Kidney Injury: A sudden decrease in kidney function caused by conditions like dehydration, severe infection, or medication side effects.
- Chronic Kidney Disease: Gradual loss of kidney function over time due to conditions like diabetes, high blood pressure, or glomerulonephritis.
- Urinary Tract Obstruction: Blockage in the urinary system, such as kidney stones or tumors, preventing normal urine flow and leading to increased creatinine levels.
- Rhabdomyolysis: Severe muscle injury or breakdown releasing myoglobin into the bloodstream, which can damage the kidneys and elevate creatinine levels.
- Pyelonephritis: Infection of the kidneys, usually caused by bacteria traveling up from the bladder, leading to inflammation and impaired kidney function.
- Nephrotic Syndrome: A kidney disorder characterized by excessive protein loss in urine, resulting in low protein levels and elevated creatinine.
- Glomerulonephritis: Inflammation of the glomeruli, the tiny blood vessels in the kidneys, often caused by immune system disorders or infections.
- Hemolytic Uremic Syndrome: A condition where the red blood cells are destroyed and clog the kidneys, leading to kidney failure and increased creatinine levels.
- Tubular Necrosis: Damage to the kidney tubules, typically caused by ischemia or toxins, resulting in reduced kidney function and elevated creatinine.
- Hepatorenal Syndrome: Kidney dysfunction that occurs as a complication of advanced liver disease, leading to impaired kidney function and increased creatinine.
What other tests should be done if creatinine level is 7.5?
Serum Electrolytes
The Serum Electrolytes test is important in this case because it helps evaluate the balance of minerals like sodium, potassium, and chloride in the body, which can be affected by kidney dysfunction. Abnormal levels of these electrolytes can indicate dehydration, impaired kidney function, or other medical conditions that may contribute to the elevated creatinine level. Monitoring electrolyte levels is crucial for managing and treating kidney disease.
Blood Urea
The blood urea test is important because it measures the amount of urea nitrogen in the blood, which is a waste product produced by the liver during protein metabolism. A high creatinine level indicates impaired kidney function, and the blood urea test helps to confirm the diagnosis by assessing the kidney's ability to filter waste products like urea from the blood.
Estimated GFR
The Estimated GFR (glomerular filtration rate) test is important in assessing kidney function because it provides an estimation of how well the kidneys are filtering waste from the blood. A creatinine level of 7.5 mg/dl indicates severe kidney dysfunction, but the Estimated GFR test can give a more accurate measure of overall kidney function and help determine the appropriate treatment or management plan. It is a crucial tool in monitoring and diagnosing kidney disease.
HBA1C
The HbA1c test is important in this scenario as it measures the average blood sugar levels over the past 2-3 months, providing insight into long-term glycemic control. This test can help diagnose and monitor diabetes, which is a common cause of kidney damage leading to high levels of creatinine. By evaluating the HbA1c levels, healthcare professionals can assess the effectiveness of diabetes management and potential risks to kidney function.
LDH
The LDH test is important in this case because it helps assess kidney function. Elevated levels of LDH (lactate dehydrogenase) can indicate renal impairment and damage to the kidneys. Therefore, it can provide valuable information in determining the severity and progression of kidney disease in individuals with a high creatinine level of 7.5 mg/dl.
Random Sugar
The Random Sugar test is important because it helps determine if the high creatinine level is due to uncontrolled diabetes, which can lead to kidney damage. It is a simple and quick test that measures blood glucose levels at any time of the day, providing immediate information about blood sugar control. Managing blood sugar levels is crucial in preventing further complications and improving kidney function.
What is the relation between creatinine and kidney function?
Creatinine, a chemical generated within the body at a consistent pace, undergoes complete elimination by the kidney in urine. When kidney function is impacted by various factors, creatinine levels experience an upsurge. Consequently, creatinine serves as a highly beneficial approach to assess the efficiency of renal function.
Why do doctors ask for GFR if my creatinine level is 7.5?
Glomerular Filtration Rate or GFR is the rate at which a given volume of blood is cleared of any substance every unit of time. This basically is a measure of the filtration capacity of the kidney. Even a small reduction in GFR can have consequences in patients who already have comorbidities. The GFR is calculated from the level of creatinine in the blood using a variety of equations like the MDRD equation given as follows : GFR (mL/min/1.73 m2) = 175 × (Scr)-1.154 × (Age)-0.203 × (0.742 if female) × (1.212 if African American). Using this formula the value of GFR can be calculated just by knowing the level of creatinine in the blood.
What is my GFR if my creatinine level is 7.5?
Estimated Glomerular Filtration Rate (GFR) for a creatinine value of 7.5
| Age in Years | Estimated Glomerular Filtration Rate (GFR) | GFR Grade |
|---|---|---|
| 18 yrs | Male : 9.51 mL/min/1.73 m2 Female : 7.06 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 19 yrs | Male : 9.41 mL/min/1.73 m2 Female : 6.98 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 20 yrs | Male : 9.31 mL/min/1.73 m2 Female : 6.91 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 21 yrs | Male : 9.22 mL/min/1.73 m2 Female : 6.84 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 22 yrs | Male : 9.13 mL/min/1.73 m2 Female : 6.78 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 23 yrs | Male : 9.05 mL/min/1.73 m2 Female : 6.72 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 24 yrs | Male : 8.98 mL/min/1.73 m2 Female : 6.66 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 25 yrs | Male : 8.9 mL/min/1.73 m2 Female : 6.6 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 26 yrs | Male : 8.83 mL/min/1.73 m2 Female : 6.55 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 27 yrs | Male : 8.76 mL/min/1.73 m2 Female : 6.5 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 28 yrs | Male : 8.7 mL/min/1.73 m2 Female : 6.45 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 29 yrs | Male : 8.64 mL/min/1.73 m2 Female : 6.41 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 30 yrs | Male : 8.58 mL/min/1.73 m2 Female : 6.36 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 31 yrs | Male : 8.52 mL/min/1.73 m2 Female : 6.32 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 32 yrs | Male : 8.47 mL/min/1.73 m2 Female : 6.28 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 33 yrs | Male : 8.41 mL/min/1.73 m2 Female : 6.24 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 34 yrs | Male : 8.36 mL/min/1.73 m2 Female : 6.2 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 35 yrs | Male : 8.31 mL/min/1.73 m2 Female : 6.17 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 36 yrs | Male : 8.27 mL/min/1.73 m2 Female : 6.13 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 37 yrs | Male : 8.22 mL/min/1.73 m2 Female : 6.1 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 38 yrs | Male : 8.18 mL/min/1.73 m2 Female : 6.07 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 39 yrs | Male : 8.13 mL/min/1.73 m2 Female : 6.03 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 40 yrs | Male : 8.09 mL/min/1.73 m2 Female : 6.0 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 41 yrs | Male : 8.05 mL/min/1.73 m2 Female : 5.97 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 42 yrs | Male : 8.01 mL/min/1.73 m2 Female : 5.94 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 43 yrs | Male : 7.97 mL/min/1.73 m2 Female : 5.92 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 44 yrs | Male : 7.94 mL/min/1.73 m2 Female : 5.89 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 45 yrs | Male : 7.9 mL/min/1.73 m2 Female : 5.86 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 46 yrs | Male : 7.86 mL/min/1.73 m2 Female : 5.84 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 47 yrs | Male : 7.83 mL/min/1.73 m2 Female : 5.81 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 48 yrs | Male : 7.8 mL/min/1.73 m2 Female : 5.79 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 49 yrs | Male : 7.76 mL/min/1.73 m2 Female : 5.76 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 50 yrs | Male : 7.73 mL/min/1.73 m2 Female : 5.74 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 51 yrs | Male : 7.7 mL/min/1.73 m2 Female : 5.71 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 52 yrs | Male : 7.67 mL/min/1.73 m2 Female : 5.69 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 53 yrs | Male : 7.64 mL/min/1.73 m2 Female : 5.67 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 54 yrs | Male : 7.61 mL/min/1.73 m2 Female : 5.65 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 55 yrs | Male : 7.58 mL/min/1.73 m2 Female : 5.63 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 56 yrs | Male : 7.56 mL/min/1.73 m2 Female : 5.61 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 57 yrs | Male : 7.53 mL/min/1.73 m2 Female : 5.59 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 58 yrs | Male : 7.5 mL/min/1.73 m2 Female : 5.57 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 59 yrs | Male : 7.48 mL/min/1.73 m2 Female : 5.55 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 60 yrs | Male : 7.45 mL/min/1.73 m2 Female : 5.53 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 61 yrs | Male : 7.43 mL/min/1.73 m2 Female : 5.51 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 62 yrs | Male : 7.4 mL/min/1.73 m2 Female : 5.49 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 63 yrs | Male : 7.38 mL/min/1.73 m2 Female : 5.47 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 64 yrs | Male : 7.35 mL/min/1.73 m2 Female : 5.46 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 65 yrs | Male : 7.33 mL/min/1.73 m2 Female : 5.44 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 66 yrs | Male : 7.31 mL/min/1.73 m2 Female : 5.42 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 67 yrs | Male : 7.29 mL/min/1.73 m2 Female : 5.41 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 68 yrs | Male : 7.26 mL/min/1.73 m2 Female : 5.39 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 69 yrs | Male : 7.24 mL/min/1.73 m2 Female : 5.37 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 70 yrs | Male : 7.22 mL/min/1.73 m2 Female : 5.36 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 71 yrs | Male : 7.2 mL/min/1.73 m2 Female : 5.34 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 72 yrs | Male : 7.18 mL/min/1.73 m2 Female : 5.33 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 73 yrs | Male : 7.16 mL/min/1.73 m2 Female : 5.31 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 74 yrs | Male : 7.14 mL/min/1.73 m2 Female : 5.3 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 75 yrs | Male : 7.12 mL/min/1.73 m2 Female : 5.28 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 76 yrs | Male : 7.1 mL/min/1.73 m2 Female : 5.27 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 77 yrs | Male : 7.08 mL/min/1.73 m2 Female : 5.26 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 78 yrs | Male : 7.07 mL/min/1.73 m2 Female : 5.24 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 79 yrs | Male : 7.05 mL/min/1.73 m2 Female : 5.23 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 80 yrs | Male : 7.03 mL/min/1.73 m2 Female : 5.22 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 81 yrs | Male : 7.01 mL/min/1.73 m2 Female : 5.2 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 82 yrs | Male : 6.99 mL/min/1.73 m2 Female : 5.19 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 83 yrs | Male : 6.98 mL/min/1.73 m2 Female : 5.18 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 84 yrs | Male : 6.96 mL/min/1.73 m2 Female : 5.16 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 85 yrs | Male : 6.94 mL/min/1.73 m2 Female : 5.15 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 86 yrs | Male : 6.93 mL/min/1.73 m2 Female : 5.14 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 87 yrs | Male : 6.91 mL/min/1.73 m2 Female : 5.13 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 88 yrs | Male : 6.89 mL/min/1.73 m2 Female : 5.12 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 89 yrs | Male : 6.88 mL/min/1.73 m2 Female : 5.1 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 90 yrs | Male : 6.86 mL/min/1.73 m2 Female : 5.09 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 91 yrs | Male : 6.85 mL/min/1.73 m2 Female : 5.08 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 92 yrs | Male : 6.83 mL/min/1.73 m2 Female : 5.07 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 93 yrs | Male : 6.82 mL/min/1.73 m2 Female : 5.06 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 94 yrs | Male : 6.8 mL/min/1.73 m2 Female : 5.05 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 95 yrs | Male : 6.79 mL/min/1.73 m2 Female : 5.04 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
References
Authorotative articles on serum creatinine
Recommended Tests
The following tests are recommeded as additional investigations for a creatinine of 7.5
HBA1C
Visit HBA1C Test to know more
Electrolytes
Visit Electrolytes to know more
Kidney Profile
Visit Kidney Profile to know more
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