Creatinine 8.1 mg/dl means : causes, treatment, GFR calculation
In this article we discuss what a creatinine value of 8.1 mg /dl means, what are its causes and how to calculate your estimated Glomerular Filtration Rate based on the GFR, as well its implications on your kidney health. We also answer the question about whether a Creatinine level of 8.1 is dangerous, good or bad.Published Date : 2023-07-14T00:31:57.337Z
Updated Date : 2024-04-11T19:29:34.151+05:30
Table of Contents
What is Creatinine?
How is creatinine measured?
What does a creatinine of 8.1 mg/dl mean in men?
What does a creatinine of 8.1 mg/dl mean in women?
Is creatinine 8.1 dangerous?
What is the normal range and is a creatinine of 8.1 mg/dl normal?
What could cause a creatinine level of 8.1?
What other tests should be done if creatinine level is 8.1?
What is the relation between creatinine and kidney function?
Why do doctors ask for GFR if my creatinine level is 8.1?
What is my GFR if my creatinine level is 8.1?
References
Recommended Tests
What is Creatinine?
Serum creatinine is a substance that is naturally produced in our bodies as a leftover product when our muscles use up a compound called creatine phosphate. It's like a little waste product that our muscles create. Interestingly, our bodies make this substance at a steady rate, so it's always present in our blood. However, the amount of serum creatinine can vary depending on how much muscle we have. Men tend to have more muscle than women, so they usually have higher levels of serum creatinine. On the other hand, during pregnancy, the levels of serum creatinine tend to be lower.1
How is creatinine measured?
A serum creatinine lab test is a common blood test used to measure the amount of creatinine in your blood. Before the test, it's important to follow pretest preparation, such as avoiding certain medications and fasting for a certain period of time. During the lab test, a small amount of blood is drawn from your arm using a needle. The blood sample is then sent to the lab, where it undergoes a process called centrifugation. This spins the blood at a high speed, separating the liquid part, called serum, from the cells. Once the serum is obtained, the lab technicians use a machine called a spectrophotometer to measure the concentration of creatinine. The spectrophotometer shines a beam of light onto the serum sample and measures how much light is absorbed or reflected. Based on this, it calculates the creatinine concentration in your blood, which helps doctors assess your kidney function.
What does a creatinine of 8.1 mg/dl mean in men?
The normal range for creatinine in women is between 0.73 and 1.18. A creatinine value of 8.1 mg/dl is considered very dangerous. It is strongly recommended that you go to the hospital right away and you may need dialysis. Do not try to treat yourself.3,4
What does a creatinine of 8.1 mg/dl mean in women?
The normal range for creatinine in women is between 0.55 and 1.02. If your creatinine level is 8.1 mg/dl, it is considered very dangerous. It is strongly recommended that you go to the hospital right away and you may need dialysis treatment. It is important not to try to treat yourself.3,4
Is creatinine 8.1 dangerous?
A creatinine of may be dangerous depending on your gender and age. The tables below highlight the likelihood of a creatinine of being dangerous for different age groups in both men and women. We provide the following tables, based on the estimated GFR corresponding to the value of creatinine.
Table of danger posed by Creatinine 8.1 in male across different ages
| Age Group | Is Creatinne of 8.1 dangerous? |
|---|---|
| 25yrs - 95 yrs | very dangerous, Get immediate medical advice and treatment. |
Table of danger posed by Creatinine 8.1 in female across different ages
| Age Group | Is Creatinne of 8.1 dangerous? |
|---|---|
| 25yrs - 95 yrs | very dangerous, Get immediate medical advice and treatment. |
What is the normal range and is a creatinine of 8.1 mg/dl normal?
The normal range for creatinine in men is 0.73 to 1.18 mg/dl, and in women it is 0.55 to 1.02 mg/dl2. Based on these ranges, a creatinine level of 8.1 is considered abnormal.
What could cause a creatinine level of 8.1?
- Acute kidney injury: A sudden and severe decrease in kidney function, often caused by dehydration, infection, or medication side effects.
- Chronic kidney disease: A long-term condition where the kidneys gradually lose their function, usually due to conditions like high blood pressure or diabetes.
- Urinary tract obstruction: Blockage in the urinary tract, such as from kidney stones or an enlarged prostate, can lead to elevated creatinine levels.
- Glomerulonephritis: Inflammation of the kidney's filtering units, known as glomeruli, which can impair their function and increase creatinine levels.
- Polycystic kidney disease: Inherited disorder causing fluid-filled cysts to develop in the kidneys, leading to kidney damage and elevated creatinine levels.
- Interstitial nephritis: Inflammation of the kidney's tubules and surrounding structures, often caused by medications, infections, or autoimmune disorders.
- Nephrotic syndrome: A condition characterized by excessive protein loss in urine, resulting in decreased kidney function and elevated creatinine levels.
- Rhabdomyolysis: A breakdown of muscle tissue that releases harmful substances into the bloodstream, potentially causing kidney damage and elevated creatinine levels.
- Hemolytic uremic syndrome: A rare condition where red blood cells are destroyed, leading to kidney injury and elevated creatinine levels.
- Renal artery stenosis: Narrowing of the arteries that supply blood to the kidneys, resulting in reduced kidney function and increased creatinine levels.
What other tests should be done if creatinine level is 8.1?
Serum Electrolytes
The Serum Electrolytes test is important in this case as it helps evaluate the levels of essential electrolytes such as sodium, potassium, and chloride in the blood, which can be affected by kidney dysfunction. Elevated creatinine levels indicate impaired kidney function, and the Serum Electrolytes test can provide additional information about the patient's electrolyte balance, aiding in the diagnosis and management of renal diseases.
Blood Urea
The blood urea test is important because it measures the level of urea nitrogen in the blood, which is a waste product of protein metabolism. A high creatinine level, like 8.1 mg/dl, indicates reduced kidney function, and the blood urea test helps to confirm kidney dysfunction by assessing the efficiency of the kidneys in removing waste products like urea from the blood. The test helps in diagnosing and monitoring conditions such as kidney disease, dehydration, and certain liver diseases.
Estimated GFR
The estimated glomerular filtration rate (eGFR) test is important because it provides an estimate of how well the kidneys are functioning to filter waste products from the blood. A creatinine level of 8.1 mg/dl indicates severe kidney dysfunction, but the eGFR test can help determine the stage of kidney disease and guide treatment decisions. It is a valuable tool for monitoring kidney health and assessing the need for interventions such as medication adjustments or dialysis.
HBA1C
The HbA1c test is important in this case because it measures the average blood sugar levels over the past 2-3 months, providing a broader picture of long-term glycemic control. It can help determine if the high creatinine level is due to uncontrolled diabetes, which can cause kidney damage. Monitoring HbA1c levels enables healthcare providers to adjust treatment plans and prevent further complications.
LDH
The LDH test is important in this case because it can help determine the cause of the elevated creatinine levels. LDH levels are often elevated in conditions such as kidney damage or dysfunction, and can provide additional information about the severity of the condition. Monitoring LDH levels alongside creatinine can help healthcare professionals make better treatment decisions for the patient.
Random Sugar
The Random Sugar test is important in this case because it helps assess the patient's blood glucose levels at any given time, regardless of when they last ate. Elevated creatinine levels can be indicative of impaired kidney function, which may affect the body's ability to regulate blood sugar levels. Therefore, a Random Sugar test can provide valuable information in determining if kidney dysfunction is impacting the patient's glucose control.
What is the relation between creatinine and kidney function?
Creatinine, a chemical synthesized within the body, maintains a consistent production rate. The kidney, responsible for eliminating creatinine through urine filtration, encounters a predicament when its functionality becomes compromised. Consequently, creatinine concentrations surge, rendering it an invaluable tool for evaluating kidney performance.
Why do doctors ask for GFR if my creatinine level is 8.1?
Glomerular Filtration Rate or GFR is the rate at which a given volume of blood is cleared of any substance every unit of time. This basically is a measure of the filtration capacity of the kidney. Even a small reduction in GFR can have consequences in patients who already have comorbidities. The GFR is calculated from the level of creatinine in the blood using a variety of equations like the MDRD equation given as follows : GFR (mL/min/1.73 m2) = 175 × (Scr)-1.154 × (Age)-0.203 × (0.742 if female) × (1.212 if African American). Using this formula the value of GFR can be calculated just by knowing the level of creatinine in the blood.
What is my GFR if my creatinine level is 8.1?
Estimated Glomerular Filtration Rate (GFR) for a creatinine value of 8.1
| Age in Years | Estimated Glomerular Filtration Rate (GFR) | GFR Grade |
|---|---|---|
| 18 yrs | Male : 8.71 mL/min/1.73 m2 Female : 6.46 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 19 yrs | Male : 8.61 mL/min/1.73 m2 Female : 6.39 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 20 yrs | Male : 8.52 mL/min/1.73 m2 Female : 6.32 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 21 yrs | Male : 8.44 mL/min/1.73 m2 Female : 6.26 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 22 yrs | Male : 8.36 mL/min/1.73 m2 Female : 6.2 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 23 yrs | Male : 8.28 mL/min/1.73 m2 Female : 6.15 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 24 yrs | Male : 8.21 mL/min/1.73 m2 Female : 6.09 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 25 yrs | Male : 8.14 mL/min/1.73 m2 Female : 6.04 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 26 yrs | Male : 8.08 mL/min/1.73 m2 Female : 6.0 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 27 yrs | Male : 8.02 mL/min/1.73 m2 Female : 5.95 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 28 yrs | Male : 7.96 mL/min/1.73 m2 Female : 5.91 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 29 yrs | Male : 7.9 mL/min/1.73 m2 Female : 5.86 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 30 yrs | Male : 7.85 mL/min/1.73 m2 Female : 5.82 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 31 yrs | Male : 7.8 mL/min/1.73 m2 Female : 5.79 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 32 yrs | Male : 7.75 mL/min/1.73 m2 Female : 5.75 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 33 yrs | Male : 7.7 mL/min/1.73 m2 Female : 5.71 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 34 yrs | Male : 7.65 mL/min/1.73 m2 Female : 5.68 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 35 yrs | Male : 7.61 mL/min/1.73 m2 Female : 5.64 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 36 yrs | Male : 7.56 mL/min/1.73 m2 Female : 5.61 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 37 yrs | Male : 7.52 mL/min/1.73 m2 Female : 5.58 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 38 yrs | Male : 7.48 mL/min/1.73 m2 Female : 5.55 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 39 yrs | Male : 7.44 mL/min/1.73 m2 Female : 5.52 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 40 yrs | Male : 7.4 mL/min/1.73 m2 Female : 5.49 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 41 yrs | Male : 7.37 mL/min/1.73 m2 Female : 5.47 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 42 yrs | Male : 7.33 mL/min/1.73 m2 Female : 5.44 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 43 yrs | Male : 7.3 mL/min/1.73 m2 Female : 5.41 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 44 yrs | Male : 7.26 mL/min/1.73 m2 Female : 5.39 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 45 yrs | Male : 7.23 mL/min/1.73 m2 Female : 5.36 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 46 yrs | Male : 7.2 mL/min/1.73 m2 Female : 5.34 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 47 yrs | Male : 7.16 mL/min/1.73 m2 Female : 5.32 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 48 yrs | Male : 7.13 mL/min/1.73 m2 Female : 5.29 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 49 yrs | Male : 7.1 mL/min/1.73 m2 Female : 5.27 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 50 yrs | Male : 7.08 mL/min/1.73 m2 Female : 5.25 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 51 yrs | Male : 7.05 mL/min/1.73 m2 Female : 5.23 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 52 yrs | Male : 7.02 mL/min/1.73 m2 Female : 5.21 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 53 yrs | Male : 6.99 mL/min/1.73 m2 Female : 5.19 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 54 yrs | Male : 6.97 mL/min/1.73 m2 Female : 5.17 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 55 yrs | Male : 6.94 mL/min/1.73 m2 Female : 5.15 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 56 yrs | Male : 6.91 mL/min/1.73 m2 Female : 5.13 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 57 yrs | Male : 6.89 mL/min/1.73 m2 Female : 5.11 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 58 yrs | Male : 6.87 mL/min/1.73 m2 Female : 5.09 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 59 yrs | Male : 6.84 mL/min/1.73 m2 Female : 5.08 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 60 yrs | Male : 6.82 mL/min/1.73 m2 Female : 5.06 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 61 yrs | Male : 6.8 mL/min/1.73 m2 Female : 5.04 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 62 yrs | Male : 6.77 mL/min/1.73 m2 Female : 5.03 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 63 yrs | Male : 6.75 mL/min/1.73 m2 Female : 5.01 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 64 yrs | Male : 6.73 mL/min/1.73 m2 Female : 4.99 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 65 yrs | Male : 6.71 mL/min/1.73 m2 Female : 4.98 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 66 yrs | Male : 6.69 mL/min/1.73 m2 Female : 4.96 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 67 yrs | Male : 6.67 mL/min/1.73 m2 Female : 4.95 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 68 yrs | Male : 6.65 mL/min/1.73 m2 Female : 4.93 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 69 yrs | Male : 6.63 mL/min/1.73 m2 Female : 4.92 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 70 yrs | Male : 6.61 mL/min/1.73 m2 Female : 4.9 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 71 yrs | Male : 6.59 mL/min/1.73 m2 Female : 4.89 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 72 yrs | Male : 6.57 mL/min/1.73 m2 Female : 4.88 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 73 yrs | Male : 6.55 mL/min/1.73 m2 Female : 4.86 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 74 yrs | Male : 6.53 mL/min/1.73 m2 Female : 4.85 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 75 yrs | Male : 6.52 mL/min/1.73 m2 Female : 4.84 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 76 yrs | Male : 6.5 mL/min/1.73 m2 Female : 4.82 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 77 yrs | Male : 6.48 mL/min/1.73 m2 Female : 4.81 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 78 yrs | Male : 6.46 mL/min/1.73 m2 Female : 4.8 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 79 yrs | Male : 6.45 mL/min/1.73 m2 Female : 4.78 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 80 yrs | Male : 6.43 mL/min/1.73 m2 Female : 4.77 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 81 yrs | Male : 6.42 mL/min/1.73 m2 Female : 4.76 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 82 yrs | Male : 6.4 mL/min/1.73 m2 Female : 4.75 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 83 yrs | Male : 6.38 mL/min/1.73 m2 Female : 4.74 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 84 yrs | Male : 6.37 mL/min/1.73 m2 Female : 4.73 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 85 yrs | Male : 6.35 mL/min/1.73 m2 Female : 4.71 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 86 yrs | Male : 6.34 mL/min/1.73 m2 Female : 4.7 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 87 yrs | Male : 6.32 mL/min/1.73 m2 Female : 4.69 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 88 yrs | Male : 6.31 mL/min/1.73 m2 Female : 4.68 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 89 yrs | Male : 6.29 mL/min/1.73 m2 Female : 4.67 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 90 yrs | Male : 6.28 mL/min/1.73 m2 Female : 4.66 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 91 yrs | Male : 6.27 mL/min/1.73 m2 Female : 4.65 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 92 yrs | Male : 6.25 mL/min/1.73 m2 Female : 4.64 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 93 yrs | Male : 6.24 mL/min/1.73 m2 Female : 4.63 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 94 yrs | Male : 6.22 mL/min/1.73 m2 Female : 4.62 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 95 yrs | Male : 6.21 mL/min/1.73 m2 Female : 4.61 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
References
Authorotative articles on serum creatinine
Recommended Tests
The following tests are recommeded as additional investigations for a creatinine of 8.1
HBA1C
Visit HBA1C Test to know more
Electrolytes
Visit Electrolytes to know more
Kidney Profile
Visit Kidney Profile to know more
Reviewed By - Dr.Bhargav Raut
Dr.Bhargav Raut is a qualified Pathologist, with over 5 years of experience in the field
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