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Creatinine 8.2 mg/dl means : causes, treatment, GFR calculation

In this article we discuss what a creatinine value of 8.2 mg /dl means, what are its causes and how to calculate your estimated Glomerular Filtration Rate based on the GFR, as well its implications on your kidney health. We also answer the question about whether a Creatinine level of 8.2 is dangerous, good or bad.
Updated Date : 2024-04-11T19:29:34.183+05:30

What is Creatinine?

Serum creatinine is a substance that our bodies make as a result of a chemical called creatine phosphate, which is found in our muscles. It is produced consistently at a steady rate, meaning it doesn't change much over time. The amount of serum creatinine we have in our blood is influenced by the amount of muscle we have - so people with more muscle tend to have higher levels. Additionally, men usually have higher levels of serum creatinine compared to women, while pregnant women tend to have lower levels.1

How is creatinine measured?

A serum creatinine lab test is a simple blood test that helps doctors measure the level of creatinine in your body. Before the test, it is important to follow some pretest preparations. This includes avoiding certain medications that can affect the results, fasting for a few hours, and drinking plenty of water. In the lab, a small sample of blood is taken from your arm using a needle. This blood is then analyzed to measure the concentration of creatinine, which is a waste product produced by our muscles.

What does a creatinine of 8.2 mg/dl mean in men?

The normal range for creatinine in women is 0.73-1.18. If your creatinine level is 8.2 mg/dl, it is considered very dangerous. It is highly recommended that you go to the hospital right away and you may need dialysis. Do not try to treat yourself.3,4

What does a creatinine of 8.2 mg/dl mean in women?

If your creatinine level is 8.2 mg/dl, it is very dangerous and could be life-threatening. It is crucial that you go to the hospital right away. You may need to undergo dialysis, and it is important not to try treating yourself at home.3,4

Is creatinine 8.2 dangerous?

A creatinine of may be dangerous depending on your gender and age. The tables below highlight the likelihood of a creatinine of being dangerous for different age groups in both men and women. We provide the following tables, based on the estimated GFR corresponding to the value of creatinine.

Table of danger posed by Creatinine 8.2 in male across different ages
Age Group Is Creatinne of 8.2 dangerous?
25yrs - 95 yrs very dangerous, Get immediate medical advice and treatment.
Table of danger posed by Creatinine 8.2 in female across different ages
Age Group Is Creatinne of 8.2 dangerous?
25yrs - 95 yrs very dangerous, Get immediate medical advice and treatment.

What is the normal range and is a creatinine of 8.2 mg/dl normal?

The normal range for creatinine in men is 0.73 to 1.18 mg/dl, and in women it is 0.55 to 1.02 mg/dl2. Based on these ranges, a creatinine level of 8.2 is considered abnormal.

What could cause a creatinine level of 8.2?

  1. Acute kidney injury: Sudden loss of kidney function due to various causes such as dehydration, kidney infections, or certain medications.
  2. Chronic kidney disease: Progressive and irreversible damage to the kidneys over a long period, often caused by conditions like diabetes or high blood pressure.
  3. Urinary tract obstruction: Blockage in the urinary tract that prevents normal urine flow, leading to increased creatinine levels.
  4. Nephrotic syndrome: Kidney disorder characterized by increased leakage of protein in urine, causing damage to the kidneys.
  5. Glomerulonephritis: Inflammation of the kidney's filtering units (glomeruli) that can impair kidney function.
  6. Rhabdomyolysis: Breakdown of muscle tissue, releasing toxic substances into the bloodstream and affecting kidney function.
  7. Hemolytic uremic syndrome: A rare condition where red blood cells are destroyed and can clog the kidneys, leading to kidney failure.
  8. Polycystic kidney disease: Inherited condition causing the formation of cysts in the kidneys, leading to impaired kidney function.
  9. Tubulointerstitial nephritis: Inflammation of the tubules and interstitium in the kidneys, often caused by medications or infections.
  10. Renal artery stenosis: Narrowing of the arteries that supply blood to the kidneys, resulting in reduced kidney function.

What other tests should be done if creatinine level is 8.2?

Serum Electrolytes

The Serum Electrolytes test is important in this case because it helps to assess the balance of electrolytes in the body, such as sodium, potassium, and chloride. An elevated creatinine level can indicate kidney dysfunction, and the Serum Electrolytes test can provide valuable information about the kidney's ability to regulate electrolyte levels. Monitoring electrolyte imbalances is crucial as they can lead to serious complications, including cardiac arrhythmias and neurological disturbances.

Blood Urea

The Blood Urea test is important because it measures the amount of urea nitrogen in the blood, which helps assess kidney function. In the case of a creatinine level of 8.2 mg/dl, a Blood Urea test is crucial as it can provide additional information about kidney health, such as indicating the presence of urea build-up due to impaired kidney function or other underlying conditions. This test can help diagnose and monitor kidney disease and guide treatment decisions.

Estimated GFR

The estimated glomerular filtration rate (eGFR) test is important because it helps assess kidney function by estimating the amount of blood filtered by the kidneys per minute. A creatinine level of 8.2 mg/dl indicates severe kidney impairment, but eGFR provides a more accurate assessment of the extent of kidney damage and helps guide treatment decisions, such as dialysis or transplantation.

HBA1C

The HBA1C test is important in this case as it measures the average blood sugar levels over the past three months, providing valuable information about long-term glucose control. It helps in evaluating the risk and management of diabetes, which can have a significant impact on kidney function. Monitoring HBA1C levels can aid in preventing further kidney damage and managing the overall health of the patient.

LDH

The LDH test is important in this case because it helps evaluate kidney function and assess the severity of kidney damage. LDH levels can be elevated in conditions such as acute kidney injury or chronic kidney disease, providing valuable information for determining appropriate treatment strategies. Monitoring LDH levels alongside creatinine levels can help healthcare professionals better understand the extent of kidney impairment and guide patient management decisions.

Random Sugar

The Random Sugar test is important because it helps evaluate blood glucose levels at any given time, which is crucial in detecting and diagnosing diabetes. In this case, a high creatinine level of 8.2 mg/dl indicates potential kidney dysfunction, which can be a complication of uncontrolled diabetes. Therefore, the Random Sugar test can provide valuable information for managing diabetes and monitoring kidney health.

What is the relation between creatinine and kidney function?

Creatinine, a chemical generated within the body consistently, undergoes complete elimination by the kidney via urine filtration. Whenever the kidney's performance is hindered by any underlying factors, there is a surge in creatinine levels. Consequently, creatinine emerges as a highly valuable means to evaluate the efficiency of renal function.

Why do doctors ask for GFR if my creatinine level is 8.2?

Glomerular Filtration Rate or GFR is the rate at which a given volume of blood is cleared of any substance every unit of time. This basically is a measure of the filtration capacity of the kidney. Even a small reduction in GFR can have consequences in patients who already have comorbidities. The GFR is calculated from the level of creatinine in the blood using a variety of equations like the MDRD equation given as follows : GFR (mL/min/1.73 m2) = 175 × (Scr)-1.154 × (Age)-0.203 × (0.742 if female) × (1.212 if African American). Using this formula the value of GFR can be calculated just by knowing the level of creatinine in the blood.

What is my GFR if my creatinine level is 8.2?

Estimated Glomerular Filtration Rate (GFR) for a creatinine value of 8.2
Age in Years Estimated Glomerular Filtration Rate (GFR) GFR Grade
18 yrsMale : 8.58 mL/min/1.73 m2
Female : 6.37 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
19 yrsMale : 8.49 mL/min/1.73 m2
Female : 6.3 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
20 yrsMale : 8.4 mL/min/1.73 m2
Female : 6.23 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
21 yrsMale : 8.32 mL/min/1.73 m2
Female : 6.17 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
22 yrsMale : 8.24 mL/min/1.73 m2
Female : 6.11 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
23 yrsMale : 8.17 mL/min/1.73 m2
Female : 6.06 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
24 yrsMale : 8.1 mL/min/1.73 m2
Female : 6.01 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
25 yrsMale : 8.03 mL/min/1.73 m2
Female : 5.96 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
26 yrsMale : 7.97 mL/min/1.73 m2
Female : 5.91 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
27 yrsMale : 7.91 mL/min/1.73 m2
Female : 5.87 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
28 yrsMale : 7.85 mL/min/1.73 m2
Female : 5.82 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
29 yrsMale : 7.79 mL/min/1.73 m2
Female : 5.78 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
30 yrsMale : 7.74 mL/min/1.73 m2
Female : 5.74 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
31 yrsMale : 7.69 mL/min/1.73 m2
Female : 5.7 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
32 yrsMale : 7.64 mL/min/1.73 m2
Female : 5.67 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
33 yrsMale : 7.59 mL/min/1.73 m2
Female : 5.63 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
34 yrsMale : 7.54 mL/min/1.73 m2
Female : 5.6 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
35 yrsMale : 7.5 mL/min/1.73 m2
Female : 5.56 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
36 yrsMale : 7.46 mL/min/1.73 m2
Female : 5.53 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
37 yrsMale : 7.42 mL/min/1.73 m2
Female : 5.5 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
38 yrsMale : 7.38 mL/min/1.73 m2
Female : 5.47 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
39 yrsMale : 7.34 mL/min/1.73 m2
Female : 5.44 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
40 yrsMale : 7.3 mL/min/1.73 m2
Female : 5.42 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
41 yrsMale : 7.26 mL/min/1.73 m2
Female : 5.39 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
42 yrsMale : 7.23 mL/min/1.73 m2
Female : 5.36 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
43 yrsMale : 7.19 mL/min/1.73 m2
Female : 5.34 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
44 yrsMale : 7.16 mL/min/1.73 m2
Female : 5.31 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
45 yrsMale : 7.13 mL/min/1.73 m2
Female : 5.29 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
46 yrsMale : 7.1 mL/min/1.73 m2
Female : 5.26 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
47 yrsMale : 7.06 mL/min/1.73 m2
Female : 5.24 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
48 yrsMale : 7.03 mL/min/1.73 m2
Female : 5.22 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
49 yrsMale : 7.0 mL/min/1.73 m2
Female : 5.2 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
50 yrsMale : 6.98 mL/min/1.73 m2
Female : 5.18 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
51 yrsMale : 6.95 mL/min/1.73 m2
Female : 5.16 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
52 yrsMale : 6.92 mL/min/1.73 m2
Female : 5.14 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
53 yrsMale : 6.89 mL/min/1.73 m2
Female : 5.12 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
54 yrsMale : 6.87 mL/min/1.73 m2
Female : 5.1 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
55 yrsMale : 6.84 mL/min/1.73 m2
Female : 5.08 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
56 yrsMale : 6.82 mL/min/1.73 m2
Female : 5.06 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
57 yrsMale : 6.79 mL/min/1.73 m2
Female : 5.04 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
58 yrsMale : 6.77 mL/min/1.73 m2
Female : 5.02 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
59 yrsMale : 6.75 mL/min/1.73 m2
Female : 5.01 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
60 yrsMale : 6.72 mL/min/1.73 m2
Female : 4.99 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
61 yrsMale : 6.7 mL/min/1.73 m2
Female : 4.97 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
62 yrsMale : 6.68 mL/min/1.73 m2
Female : 4.96 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
63 yrsMale : 6.66 mL/min/1.73 m2
Female : 4.94 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
64 yrsMale : 6.64 mL/min/1.73 m2
Female : 4.92 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
65 yrsMale : 6.61 mL/min/1.73 m2
Female : 4.91 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
66 yrsMale : 6.59 mL/min/1.73 m2
Female : 4.89 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
67 yrsMale : 6.57 mL/min/1.73 m2
Female : 4.88 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
68 yrsMale : 6.55 mL/min/1.73 m2
Female : 4.86 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
69 yrsMale : 6.53 mL/min/1.73 m2
Female : 4.85 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
70 yrsMale : 6.52 mL/min/1.73 m2
Female : 4.83 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
71 yrsMale : 6.5 mL/min/1.73 m2
Female : 4.82 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
72 yrsMale : 6.48 mL/min/1.73 m2
Female : 4.81 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
73 yrsMale : 6.46 mL/min/1.73 m2
Female : 4.79 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
74 yrsMale : 6.44 mL/min/1.73 m2
Female : 4.78 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
75 yrsMale : 6.42 mL/min/1.73 m2
Female : 4.77 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
76 yrsMale : 6.41 mL/min/1.73 m2
Female : 4.75 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
77 yrsMale : 6.39 mL/min/1.73 m2
Female : 4.74 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
78 yrsMale : 6.37 mL/min/1.73 m2
Female : 4.73 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
79 yrsMale : 6.36 mL/min/1.73 m2
Female : 4.72 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
80 yrsMale : 6.34 mL/min/1.73 m2
Female : 4.71 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
81 yrsMale : 6.33 mL/min/1.73 m2
Female : 4.69 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
82 yrsMale : 6.31 mL/min/1.73 m2
Female : 4.68 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
83 yrsMale : 6.29 mL/min/1.73 m2
Female : 4.67 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
84 yrsMale : 6.28 mL/min/1.73 m2
Female : 4.66 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
85 yrsMale : 6.26 mL/min/1.73 m2
Female : 4.65 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
86 yrsMale : 6.25 mL/min/1.73 m2
Female : 4.64 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
87 yrsMale : 6.23 mL/min/1.73 m2
Female : 4.63 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
88 yrsMale : 6.22 mL/min/1.73 m2
Female : 4.61 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
89 yrsMale : 6.21 mL/min/1.73 m2
Female : 4.6 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
90 yrsMale : 6.19 mL/min/1.73 m2
Female : 4.59 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
91 yrsMale : 6.18 mL/min/1.73 m2
Female : 4.58 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
92 yrsMale : 6.16 mL/min/1.73 m2
Female : 4.57 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
93 yrsMale : 6.15 mL/min/1.73 m2
Female : 4.56 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
94 yrsMale : 6.14 mL/min/1.73 m2
Female : 4.55 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure
95 yrsMale : 6.12 mL/min/1.73 m2
Female : 4.54 mL/min/1.73 m2
GFR Grade G5 : Kidney Failure

References

Authorotative articles on serum creatinine

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