Creatinine 8.8 mg/dl means : causes, treatment, GFR calculation
In this article we discuss what a creatinine value of 8.8 mg /dl means, what are its causes and how to calculate your estimated Glomerular Filtration Rate based on the GFR, as well its implications on your kidney health. We also answer the question about whether a Creatinine level of 8.8 is dangerous, good or bad.Published Date : 2023-07-15T00:31:57.337Z
Updated Date : 2024-04-11T19:29:34.374+05:30
Table of Contents
What is Creatinine?
How is creatinine measured?
What does a creatinine of 8.8 mg/dl mean in men?
What does a creatinine of 8.8 mg/dl mean in women?
Is creatinine 8.8 dangerous?
What is the normal range and is a creatinine of 8.8 mg/dl normal?
What could cause a creatinine level of 8.8?
What other tests should be done if creatinine level is 8.8?
What is the relation between creatinine and kidney function?
Why do doctors ask for GFR if my creatinine level is 8.8?
What is my GFR if my creatinine level is 8.8?
References
Recommended Tests
What is Creatinine?
Serum creatinine is a substance that is naturally made in our bodies as a result of a chemical called creatine phosphate found in our muscles. It is produced steadily and at a consistent rate. The amount of serum creatinine in our blood depends on how much muscle mass we have – meaning that it tends to be higher in men compared to women. Additionally, during pregnancy, the levels of serum creatinine are generally lower. So, think of serum creatinine as a byproduct of muscle activity that can vary based on factors like gender and pregnancy.1
How is creatinine measured?
A serum creatinine lab test is a simple blood test that helps doctors check how well our kidneys are working. Before the test, it is important to tell the doctor about any medications or supplements we are taking, as they can affect the results. Fasting is not usually required for this test. In the lab, a small sample of our blood is taken by a nurse or technician. They will clean our skin with an alcohol swab and then use a tiny needle to draw the blood from a vein in our arm. This may feel like a small pinch, but it is usually quick and not too painful. Once the blood sample is collected, it is sent to the lab where they measure the amount of creatinine in our blood. Creatinine is a waste product that our muscles produce and our kidneys filter out of our blood. The lab uses a machine called a spectrophotometer to measure the concentration of creatinine. The results of this test can help doctors determine if our kidneys are functioning normally or if there may be any kidney problems that need further investigation.
What does a creatinine of 8.8 mg/dl mean in men?
The normal range for creatinine in women is between 0.73 and 1.18. A creatinine value of 8.8 mg/dl is considered very dangerous. It is strongly advised that you go to the hospital immediately and you may need dialysis. Do not try to treat yourself with medication.3,4
What does a creatinine of 8.8 mg/dl mean in women?
The normal range for creatinine in women is 0.55-1.02. If your creatinine value is 8.8 mg/dl, it is considered life threatening. It is highly recommended that you go to the hospital right away and you may need dialysis. Do not try to treat yourself without medical help.3,4
Is creatinine 8.8 dangerous?
A creatinine of may be dangerous depending on your gender and age. The tables below highlight the likelihood of a creatinine of being dangerous for different age groups in both men and women. We provide the following tables, based on the estimated GFR corresponding to the value of creatinine.
Table of danger posed by Creatinine 8.8 in male across different ages
| Age Group | Is Creatinne of 8.8 dangerous? |
|---|---|
| 25yrs - 95 yrs | very dangerous, Get immediate medical advice and treatment. |
Table of danger posed by Creatinine 8.8 in female across different ages
| Age Group | Is Creatinne of 8.8 dangerous? |
|---|---|
| 25yrs - 95 yrs | very dangerous, Get immediate medical advice and treatment. |
What is the normal range and is a creatinine of 8.8 mg/dl normal?
The normal range for creatinine in men is 0.73 to 1.18 mg/dl, and in women it is 0.55 to 1.02 mg/dl2. Based on these ranges, a creatinine level of 8.8 is considered abnormal.
What could cause a creatinine level of 8.8?
- Acute kidney injury: Sudden loss of kidney function due to various reasons such as dehydration, reduced blood flow, or medication side effects.
- Chronic kidney disease: Long-term damage to the kidneys, often caused by conditions like diabetes or high blood pressure.
- Glomerulonephritis: Inflammation of the glomeruli, which are the tiny filters in the kidneys that remove waste and excess fluid from the blood.
- Urinary tract obstruction: Blockage in the urinary tract, such as kidney stones or an enlarged prostate, preventing normal urine flow and leading to elevated creatinine levels.
- Nephrotoxic medications: Certain medications, like nonsteroidal anti-inflammatory drugs (NSAIDs) or some antibiotics, can cause kidney damage and increase creatinine levels.
- Rhabdomyolysis: A condition where muscle breakdown releases a protein called myoglobin into the bloodstream, which can damage the kidneys and raise creatinine levels.
- Hemolytic uremic syndrome: A rare disorder characterized by the destruction of red blood cells, leading to kidney injury and elevated creatinine levels.
- Polycystic kidney disease: Inherited disorder causing the growth of cysts in the kidneys, gradually impairing kidney function and elevating creatinine levels.
- Interstitial nephritis: Inflammation of the kidney tubules and surrounding tissues, often caused by allergic reactions or certain medications.
- Renal artery stenosis: Narrowing of the arteries that supply blood to the kidneys, reducing kidney function and resulting in increased creatinine levels.
What other tests should be done if creatinine level is 8.8?
Serum Electrolytes
The Serum Electrolytes test is important in this case because it helps evaluate the balance of electrolytes in the body, such as sodium, potassium, and chloride. Abnormal levels of electrolytes can affect kidney function, and since the creatinine level is significantly high, it is crucial to determine if there is an electrolyte imbalance that may be contributing to kidney dysfunction. Prompt intervention and appropriate management of electrolyte imbalances can help improve kidney function and overall health.
Blood Urea
The Blood Urea test is important in this case because it helps to assess kidney function and measure the level of urea nitrogen in the blood. High levels of creatinine indicate impaired kidney function, and the Blood Urea test can provide additional information to confirm and evaluate the extent of renal dysfunction. Monitoring blood urea levels is crucial for diagnosing and managing conditions such as kidney disease, dehydration, and certain medications' side effects.
Estimated GFR
The estimated glomerular filtration rate (eGFR) test is important in assessing kidney function by estimating the rate at which the kidneys filter waste from the blood. A creatinine level of 8.8 mg/dl indicates severe kidney impairment, but the eGFR test provides a more comprehensive evaluation of kidney function, allowing for better diagnosis, treatment decisions, and monitoring of kidney disease progression. It is a crucial tool in determining the stage of chronic kidney disease and guiding appropriate interventions.
HBA1C
The HbA1c test is important in this case as it provides an indication of the average blood sugar levels over the past few months. It helps in evaluating long-term glycemic control and identifying the risk of developing diabetes or monitoring the management of existing diabetes. This information is crucial in determining the appropriate treatment plan for the patient with a high creatinine level.
LDH
The LDH test is important in this case because it can help determine the cause of the elevated creatinine level. LDH levels are often elevated in conditions such as kidney damage or muscle breakdown, which can contribute to high creatinine levels. By measuring LDH, healthcare providers can gain insights into the underlying condition causing the elevated creatinine and guide appropriate treatment.
Random Sugar
The Random Sugar test is important in this case because it helps determine the blood glucose levels at the time of testing, which can be affected by high creatinine levels. This test is crucial in evaluating the patient's overall kidney function and detecting any potential kidney disease or diabetes. Monitoring the Random Sugar levels can help guide treatment decisions and prevent complications related to high blood sugar levels.
What is the relation between creatinine and kidney function?
Creatinine, a compound manufactured within the body, maintains a steady production rate. The kidney dutifully sieves out creatinine, leaving none behind in the urine. However, when the kidney's functionality is impaired for various causes, the levels of creatinine surge. Consequently, creatinine serves as an invaluable means to assess the kidney's operation. In a nutshell, creatinine's role in gauging kidney function is undeniably significant.
Why do doctors ask for GFR if my creatinine level is 8.8?
Glomerular Filtration Rate or GFR is the rate at which a given volume of blood is cleared of any substance every unit of time. This basically is a measure of the filtration capacity of the kidney. Even a small reduction in GFR can have consequences in patients who already have comorbidities. The GFR is calculated from the level of creatinine in the blood using a variety of equations like the MDRD equation given as follows : GFR (mL/min/1.73 m2) = 175 × (Scr)-1.154 × (Age)-0.203 × (0.742 if female) × (1.212 if African American). Using this formula the value of GFR can be calculated just by knowing the level of creatinine in the blood.
What is my GFR if my creatinine level is 8.8?
Estimated Glomerular Filtration Rate (GFR) for a creatinine value of 8.8
| Age in Years | Estimated Glomerular Filtration Rate (GFR) | GFR Grade |
|---|---|---|
| 18 yrs | Male : 7.91 mL/min/1.73 m2 Female : 5.87 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 19 yrs | Male : 7.83 mL/min/1.73 m2 Female : 5.81 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 20 yrs | Male : 7.74 mL/min/1.73 m2 Female : 5.75 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 21 yrs | Male : 7.67 mL/min/1.73 m2 Female : 5.69 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 22 yrs | Male : 7.6 mL/min/1.73 m2 Female : 5.64 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 23 yrs | Male : 7.53 mL/min/1.73 m2 Female : 5.59 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 24 yrs | Male : 7.46 mL/min/1.73 m2 Female : 5.54 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 25 yrs | Male : 7.4 mL/min/1.73 m2 Female : 5.49 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 26 yrs | Male : 7.34 mL/min/1.73 m2 Female : 5.45 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 27 yrs | Male : 7.29 mL/min/1.73 m2 Female : 5.41 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 28 yrs | Male : 7.23 mL/min/1.73 m2 Female : 5.37 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 29 yrs | Male : 7.18 mL/min/1.73 m2 Female : 5.33 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 30 yrs | Male : 7.13 mL/min/1.73 m2 Female : 5.29 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 31 yrs | Male : 7.09 mL/min/1.73 m2 Female : 5.26 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 32 yrs | Male : 7.04 mL/min/1.73 m2 Female : 5.22 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 33 yrs | Male : 7.0 mL/min/1.73 m2 Female : 5.19 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 34 yrs | Male : 6.95 mL/min/1.73 m2 Female : 5.16 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 35 yrs | Male : 6.91 mL/min/1.73 m2 Female : 5.13 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 36 yrs | Male : 6.87 mL/min/1.73 m2 Female : 5.1 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 37 yrs | Male : 6.84 mL/min/1.73 m2 Female : 5.07 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 38 yrs | Male : 6.8 mL/min/1.73 m2 Female : 5.04 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 39 yrs | Male : 6.76 mL/min/1.73 m2 Female : 5.02 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 40 yrs | Male : 6.73 mL/min/1.73 m2 Female : 4.99 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 41 yrs | Male : 6.69 mL/min/1.73 m2 Female : 4.97 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 42 yrs | Male : 6.66 mL/min/1.73 m2 Female : 4.94 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 43 yrs | Male : 6.63 mL/min/1.73 m2 Female : 4.92 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 44 yrs | Male : 6.6 mL/min/1.73 m2 Female : 4.9 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 45 yrs | Male : 6.57 mL/min/1.73 m2 Female : 4.87 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 46 yrs | Male : 6.54 mL/min/1.73 m2 Female : 4.85 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 47 yrs | Male : 6.51 mL/min/1.73 m2 Female : 4.83 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 48 yrs | Male : 6.48 mL/min/1.73 m2 Female : 4.81 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 49 yrs | Male : 6.46 mL/min/1.73 m2 Female : 4.79 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 50 yrs | Male : 6.43 mL/min/1.73 m2 Female : 4.77 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 51 yrs | Male : 6.4 mL/min/1.73 m2 Female : 4.75 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 52 yrs | Male : 6.38 mL/min/1.73 m2 Female : 4.73 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 53 yrs | Male : 6.35 mL/min/1.73 m2 Female : 4.71 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 54 yrs | Male : 6.33 mL/min/1.73 m2 Female : 4.7 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 55 yrs | Male : 6.31 mL/min/1.73 m2 Female : 4.68 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 56 yrs | Male : 6.28 mL/min/1.73 m2 Female : 4.66 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 57 yrs | Male : 6.26 mL/min/1.73 m2 Female : 4.65 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 58 yrs | Male : 6.24 mL/min/1.73 m2 Female : 4.63 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 59 yrs | Male : 6.22 mL/min/1.73 m2 Female : 4.61 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 60 yrs | Male : 6.2 mL/min/1.73 m2 Female : 4.6 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 61 yrs | Male : 6.18 mL/min/1.73 m2 Female : 4.58 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 62 yrs | Male : 6.16 mL/min/1.73 m2 Female : 4.57 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 63 yrs | Male : 6.14 mL/min/1.73 m2 Female : 4.55 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 64 yrs | Male : 6.12 mL/min/1.73 m2 Female : 4.54 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 65 yrs | Male : 6.1 mL/min/1.73 m2 Female : 4.52 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 66 yrs | Male : 6.08 mL/min/1.73 m2 Female : 4.51 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 67 yrs | Male : 6.06 mL/min/1.73 m2 Female : 4.5 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 68 yrs | Male : 6.04 mL/min/1.73 m2 Female : 4.48 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 69 yrs | Male : 6.02 mL/min/1.73 m2 Female : 4.47 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 70 yrs | Male : 6.01 mL/min/1.73 m2 Female : 4.46 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 71 yrs | Male : 5.99 mL/min/1.73 m2 Female : 4.44 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 72 yrs | Male : 5.97 mL/min/1.73 m2 Female : 4.43 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 73 yrs | Male : 5.95 mL/min/1.73 m2 Female : 4.42 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 74 yrs | Male : 5.94 mL/min/1.73 m2 Female : 4.41 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 75 yrs | Male : 5.92 mL/min/1.73 m2 Female : 4.39 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 76 yrs | Male : 5.91 mL/min/1.73 m2 Female : 4.38 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 77 yrs | Male : 5.89 mL/min/1.73 m2 Female : 4.37 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 78 yrs | Male : 5.88 mL/min/1.73 m2 Female : 4.36 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 79 yrs | Male : 5.86 mL/min/1.73 m2 Female : 4.35 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 80 yrs | Male : 5.84 mL/min/1.73 m2 Female : 4.34 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 81 yrs | Male : 5.83 mL/min/1.73 m2 Female : 4.33 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 82 yrs | Male : 5.82 mL/min/1.73 m2 Female : 4.32 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 83 yrs | Male : 5.8 mL/min/1.73 m2 Female : 4.3 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 84 yrs | Male : 5.79 mL/min/1.73 m2 Female : 4.29 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 85 yrs | Male : 5.77 mL/min/1.73 m2 Female : 4.28 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 86 yrs | Male : 5.76 mL/min/1.73 m2 Female : 4.27 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 87 yrs | Male : 5.75 mL/min/1.73 m2 Female : 4.26 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 88 yrs | Male : 5.73 mL/min/1.73 m2 Female : 4.25 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 89 yrs | Male : 5.72 mL/min/1.73 m2 Female : 4.24 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 90 yrs | Male : 5.71 mL/min/1.73 m2 Female : 4.23 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 91 yrs | Male : 5.69 mL/min/1.73 m2 Female : 4.22 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 92 yrs | Male : 5.68 mL/min/1.73 m2 Female : 4.22 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 93 yrs | Male : 5.67 mL/min/1.73 m2 Female : 4.21 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 94 yrs | Male : 5.66 mL/min/1.73 m2 Female : 4.2 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
| 95 yrs | Male : 5.64 mL/min/1.73 m2 Female : 4.19 mL/min/1.73 m2 | GFR Grade G5 : Kidney Failure |
References
Authorotative articles on serum creatinine
Recommended Tests
The following tests are recommeded as additional investigations for a creatinine of 8.8
HBA1C
Visit HBA1C Test to know more
Electrolytes
Visit Electrolytes to know more
Kidney Profile
Visit Kidney Profile to know more
Reviewed By - Dr.Bhargav Raut
Dr.Bhargav Raut is a qualified Pathologist, with over 5 years of experience in the field
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