ESR 80 means : Is ESR 80 dangerous - causes, symptoms

Published Date : 2023-12-06T13:31:03.637Z

Updated Date : 2024-05-15T19:05:01.444+05:30

What is ESR?

ESR, stands for Erythrocyte Sedimentation Rate. It is the rate or speed at which red blood cells (erythrocytes) settle down to the bottom of a standardized tube. ESR measures how fast the cells go down by gravity. This speed depends on many factors like what kind of other proteins are present in the blood and in what amounts.

ESR is measured by the ESR test, a commonly performed test in many laboratories.

The test is important because it is a measure of inflammation or infection - the value of ESR is usually high in conditions like cancers, tuberculosis, infections, fevers and also in anemia and advanced age.

It is a common test in many blood test panels, and is usually done to rule out infection or inflammation as a cause of your symptoms

The test usually takes upto an hour to perform, but as far as the patient is concerned, all it needs is a single blood sample.

How is ESR measured?

ESR is measured in the laboratory. This is not a test that can be done at home. To measure ESR the laboratory will first collect a sample of blood. If you have ever had a blood test before, this will be familiar to you.

The blood is collected by inserting a small needle in your vein, and collecting about 3-4ml of blood in a tube

The blood is then filled into a glass tube, that is standardized height and width. This blood is then allowed to settle over an hour inside the tube

Over time a clear portion emerges at the upper end of the tube, and the red cells settle at the bottom

The length of the clear portion is measured and it is then entered into your report as the ESR in mm per hour

What is the normal range of ESR and how is an ESR of 80 graded?

Different sources mention slightly different normal ranges for ESR. The normal range also varies slightly based on the method of measurement. When measured by the Westergren method, the normal range for ESR is mentioned below for adult males, adult females and children.

Normal Range and Grading for Adult Males : ESR 80 mm/hr

Normal Range and Grading for Adult Women : ESR 80 mm/hr

Normal Range and Grading for Children : ESR 80 mm/hr

What does an ESR of 80 mean?

An ESR level of 80 is considered to be significantly elevated. A cause must be found for the elevated ESR, while ruling out normal or physiological causes. An ESR between 50 and 80, is definitely not normal and must be further investigated together with additional tests, that are listed in a subsequent section.

Is ESR 80 good?

An ESR of 80 is not a good value. In adults, or children this value is above normal and needs investigating.

Is ESR 80 bad?

An ESR of 80 is bad in all populations and should be further investigated.

Is ESR 80 dangerous?

An ESR of 80 is elevated but not necessarily dangerous Note that an ESR is basically a measure of the thickness of your blood and itself is not a thing or an entity. It on its own will not harm you, rather the underlying cause is what needs to be investigated.

Is ESR 80 normal?

An ESR of 80 is not normal and is classified as elevated.

What are the causes of an ESR of 80 mm/hr?

An ESR of 80 can have various causing including the following :

• Hepatitis : Hepatitis caused by the three hepatitis viruses, A, B, and C can all lead to increased ESR levels. When these viruses infect the liver, they cause inflammation and pain, as well as fever and sometimes yellow colored eyes - also called jaundice. ESR is elevated due to the fact that these diseases take a long time to heal, and are called chronic infections.
• Lymphoma : This is a type of blood cancer, that leads to increased numbers of white cells. Most cancers lead to increased ESR levels, and lymphomas are often associated with an elevated ESR.
• Thyroid Disorders : If your thyroid is not working correctly, it can cause changes in your ESR. If you have hypothyroidism(means your thyroid works too slowly), it can lead to anemia and also an increased ESR. Make sure to check your thyroid levels together with your ESR in your next blood workup.
• Inflammatory Bowel Disease : Autoimmune diseases of the intestine, are called inflammatory bowel diseases. In these diseases there are small erosions in the intestine or gut. These lead to constipation and diarrhea both. If you have Inflammatory Bowel disease you may have an increased ESR.
• Infection : ESR is more commonly elevated in chronic infections like Tuberculosis(infection by the M.Tb bacteria), leprosy, syphilis, or parasitic infestations. These infections usually cause a persistent increase in the levels of antibodies. These antibodies change the composition of the blood and as a result the ESR increases.
• Vasculitis : Vasculitis is another autoimmune disease. In this disease there is inflammation inside the blood vessels. Sometimes this affects small vessels, sometimes large ones and sometimes medium sized vessels. Blood vessels in the lungs, kidneys or even the brain can be affected. This usually leads to an increased ESR.
• Pregnancy : During pregnancy, a mother's body changes considerably, ESR is one of the measurements in the blood count that rises. Pregnancy is a state in which the mothers total volume of blood also increases, together with many other small changes. ESR also increases in pregnancy.
• HIV/AIDS : The human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS) is a viral infection that is passed by sexual contact or through shared needles, or blood transfusiosn. Patients of this disease cannot fight off infections. ESR levels are often increased, in this condition, and more so in its later stages.
• Anemia : Anemia is a condition in which the blood becomes thinner and less red. This happens due to fewer or smaller red cells. ESR is known to increase in people who are anemic. This is because the red cells, fewer and smaller in number, settle down faster. Infact, the ESR can increase to such an extent, that a correction factor is often applied to anemic patients before their ESR value is reported.
• Behçet's Disease : A rare inflammatory disorder causing blood vessel inflammation.
• Myeloma : A type of blood cancer, that affects the bones and many other organs in the body. Myelomas originate from plasma cells - cells that normally fight off infections. They cause a very big increase in ESR.
• Tissue injury : Trauma, or acute injuries, like those in a road accident or burns, may also cause the ESR to rise as a part of the generalized inflammatory process.

What are the causes for a falsely elevated ESR value of 80?

There are certain normal or physiological conditions in which the ESR May be falsely elevated or elevated without any abnormality.

• Race/Ethnicity : ESR levels have been found to be higher in blacks, as compared to whites. This difference is independent of all other factors like age, gender etc. Make sure to check with your doctor for more information.
• Surgery : Any surgery that is done on the body, will trigger an inflammatory response. Major surgeries are associated with
• Pregnancy : Pregnancy produces a physiological or natural increase in ESR. If you are pregnant, make sure that your doctor/lab uses the normal ranges of pregnancy for ESR. ESR can change by a lot during pregnancy especially in the later few months.
• Dietary Factors : Eating foods heavy in fats or cholesterol causes an increase in the ESR level, a couple of hours after the meal. This effect is probably due to the increased levels of the fats in the blood. Thus if you had your ESR test a couple of hours after a heavy meal, you may need to test it again, while fasting.
• Smoking : Heavy smokers are found to have a higher ESR level, when all other factors are adjusted for. This is probably due to the low grade of inflammation produced by the chemicals found in smoke.
• Strenuous Exercise : Sudden, intense physical activity, of any kind, can lead to an inflammatory response from the body. Inflammation can be in the muscles, joints or tendons and this can lead to a rise in ESR. Patients are advised to avoid intense activity before providing their sample for the ESR test as it can cause significant deviations from the mean.
• Altitude Changes : ESR may be reduced at higher altitudes. An increased ESR level at a high altitude, is a sign of concern, as it normally reduces at higher altitudes due to changes in hemoglobin.
• Menstrual Cycle : In females, ESR may show various fluctuations from normal during the menstrual cycle. During menses, there is a small rise in the ESR, due to the small amount of inflammation that accompanies the shedding of the uterine lining. This is expected as there is bleeding during the menstrual phase of the menstrual cycle.
• Sleep Deprivation : Staying awake for long hours, and not getting enough sleep are associated with an increase in inflammation in the body. This is also reflected in the levels of ESR, which are higher in people who suffer from sleep deprivation.
• Dehydration : Dehydration leads to increased thickness of blood, this is because water is lost, so the blood becomes hyperviscous and thick. Dehydration can lead to increased ESR, as anything that makes the blood thicker, usually causes the ESR to increase.
• Aging : If you are above 55 years of age, your ESR is expected to be higher than normal. ESR increases progressively with increased age. The rise in ESR is attributed to age related wear and tear in the body, as well as age related anemias.
• Postpartum Period : During the first week after delivery, the body is still under stress. The mother's ESR and other markers of inflammation like fibrinogen are known to remain elevated. The cause is the process of childbirth, which puts the mother's body under strain.

What does an ESR of 80 in pregnancy mean?

The normal range of ESR during pregnancy is different in the different months or trimesters of pregnancy. This is because pregnancy causes a small rise in the ESR, which is considered normal. The following table lists the normal ranges.

Trimester	Lower Limit	Upper Limit
1st	4	57
2nd	7	47
3rd	13	70

Based on these criteria, your ESR of 80 can be classified as below.
If you are in the first three months of pregnancy an ESR of 80 is elevated
If you are in the second trimester or months 3-6 of pregnancy an ESR of 80 is elevated
If you are in the third trimester or months 7-9 of pregnancy an ESR of 80 is elevated

What are the symptoms of an ESR of 80 ?

ESR itself does not cause any direct symptoms. The symptoms of ESR are due the underlying disease process. The following is a list of symptoms that may be associated with an ESR of 80 :

• Fatigue : Feeling tired all the time is a feature of several of the causes of ESR. ESR itself does not cause any symptoms. Fatigue is commonly seen in anemia, cancers, infections and autoimmune diseases, all of which are the causes of a raised ESR.
• Swollen Lymph Nodes : A very common sign seen in chronic diseases like Tuberculosis, some blood cancers are swollen lymph nodes. These are swellings in the neck region. ESR is often increased when the lymph nodes are swollen. Read about tests for swollen lymph nodes to know more.
• Abnormal Blood Counts : Changes in white blood cell count or other blood parameters.
• Dizziness : Feeling lightheaded or unsteady.
• Recurrent Infections : This means repeatedly getting infections, and it can be a sign of a deficient immune system. These disorders may produce a rise in ESR as a part of the inflammatory proceses.
• Shortness of Breath : Shortness of breath or difficulty in breathing may be due to a chest infection, allergies, pneumonia or even tuberculosis. If accompanied by a high ESR level it may be a cause of concern.
• Joint Pain : Joint pain is often seen in Arthritis and different autoimmune disease that may be causing the rise in your ESR levels. Joint pain may be in the small joints of your hands or the bigger joints like shoulders or knees. Joint pains may also be seen in some infections like dengue, which can also cause a rise in ESR. Read about tests for joint pains to know more.
• Unexplained Weight Loss : Loss of weight, without any change in your daily intake of calories or exercise is a cause of concern and is seen in many of the causes of ESR. Weight loss associated with rise in ESR is one of the cardinal signs of Tuberculosis. Tests for a sudden loss of weight may help you to learn more about your condition.
• Difficulty Sleeping : Insomnia or disrupted sleep patterns.
• Fever : Fever is often accompanied by a rise in ESR. Fever is caused by proteins released by the liver in response to inflammation. The same proteins cause a rise in ESR. Fever is a rise in temperature above normal, and is one of the most common symptoms associated with ESR and may be seen in conditions like dengue. Read more about tests for dengue here.
• Photosensitivity : Increased sensitivity to sunlight.
• Cough : Chronic cough, or coughing persistently with other symptoms may be a common symptom that is linked with a rise in ESR.
• Frequent Urination : Increased need to urinate.
• Nausea and Vomiting : Feeling of sickness and vomiting.
• Digestive Issues : Changes in your bowel habits, constipation and diarrhea ,if present, alternatingly are all signs of irritable bowel syndrome, which itself is often associated with an elevated ESR.
• Irregular Menstrual Cycles : Changes in menstrual patterns for women.
• Skin Rashes : Autoimmune diseases may show skin rashes, such as SLE. This may be one of the rarer symptoms with a high ESR level
• Neurological Symptoms : Tingling, numbness, or weakness.
• Muscle Aches : Pain in the muscles may be a sign of an inflammatory process. Muscle pain is very hard to pinpoint, but it may be the beginning of a fever or infection. ESR is sometimes increased in injuries to multiple muscles like after an accident or fall.
• Depression : Persistent feelings of sadness or hopelessness.
• Cognitive Impairment : Memory problems, may be seen in chronic diseases like HIV, which will also be seen together with a rise in ESR.
• Hair Loss : Hair loss may be seen in severe deficiencies and these may also cause a rise in ESR due to inflammation in the body.
• Night Sweats : Night sweats are a common symptom in Tuberculosis, as well as some tropical diseases. Night sweats, together with weight loss and an increased ESR are all suggestive of a chronic inflammatory process. Night sweats refer to waking up in bed, drenched in sweat, despite there being adequate cooling in the room. Tests for night sweats may shed more light on this symptom.
• Headaches : Severe headaches, especially in male patients above 50, may be a sign of an autoimmune disease of the blood vessels. If headaches are the only symptom, combined with an elevated ESR, then you should get yourself to a rheumatologist at soonest. Learn more about tests for headaches here.

Which foods can reduce an ESR of 80 mm/hr?

Based on a study by Hulander et al, eating foods that lower inflammation can lead to a lowered value of ESR. The following foods can be consumed to try to reduce inflammation.

• Fatty Fish : Fish like salmon and mackarel are rich in Long Chain and omega fatty acids. These are natural anti-inflammatory agents and have been shown to reduce inflammatory markers both before and after food intake. A diet that mixes in balanced amounts of these foods, help to reduce inflammation and consequently ESR.
• Nuts : Walnuts, contain the highest content of plant-based polyunsaturated fatty acids (PUFAs), including ALA. Other nuts are also rich in anti inflammatory chemicals that help to reduce inflammation. This brings down the ESR levels.
• Vegetables : Vegetables are rich in fiber and minerals and vitamins. All are essential components of helping to combat oxidation and infections. This helps to bring down the ESR.
• Probiotics : Probiotic foods help to reduce inflammation, and specifically Reactive Oxygen Species, that are the cause of many of the components of inflammation. Reactive Oxygen species cause damage to tissues and inflammation. Probiotics improve the gut health and help reduce inflammation contributing to reduce ESR.
• Fruits : Various fruits, including citrus fruits and berries, are packed with vitamins, minerals, and antioxidants. Fruits also contain fiber and help reduce inflammation by combating oxidation. This, combined with various vitamins help to combat inflammation and tissue damage and will consequently bring down the ESR.
• Legumes : Legumes, such as lentils and chickpeas, contain peptides, polyphenols and saponins, all of which are very potent anti-inflammatory agents. Specifically acting against chronic inflammation which is a key factor that causes an elevated ESR, legumes can help reduce ESR.

What other tests should be done with an ESR of 80 ?

For an ESR of 80, other tests can be done to further ascertain the immune status of the body, as well as rule out infections or malignancies if any.
The following table lists other tests that can be done.

Lab Tests Related to ESR

Living with an ESR of 80

An elevated ESR level is not something you should take lightly or live with. If the cause is an infection or inflammation, this should be investigated or treated. If the cause is a chronic disease or a cancer, you should get medical advice. Consulting a medical practitioner is essential if your ESR remains at 80 for a prolonged period of time.

What is the ESR to CRP ratio and why does it matter?

The ESR to CRP ratio is the ratio of the Erythryocyte Sedimentation Rate in to the C-Reactive Protein Value. The ratio has value in patients with Systemic Lupus Erythematosus. If the value is below 2 it indicates that the patient has an infection in addition to the SLE. If the value is above 15 it is more likely to be a flare up of SLE. You can find the ratio calculated for various values of CRP given your ESR value of 80

What is my ESR:CRP ratio for an ESR of 80 ?

ESR	CRP	Ratio	Means
80	1.0	80.0	More likely to be autoimmune disease flareup of SLE
80	1.5	53.3	More likely to be autoimmune disease flareup of SLE
80	2.0	40.0	More likely to be autoimmune disease flareup of SLE
80	2.5	32.0	More likely to be autoimmune disease flareup of SLE
80	3.0	26.7	More likely to be autoimmune disease flareup of SLE
80	3.5	22.9	More likely to be autoimmune disease flareup of SLE
80	4.0	20.0	More likely to be autoimmune disease flareup of SLE
80	4.5	17.8	More likely to be autoimmune disease flareup of SLE
80	5.0	16.0	More likely to be autoimmune disease flareup of SLE

References

1. Dapper DV, Didia BC. Haemorheological changes during the menstrual cycle. East Afr Med J. 2002 Apr;79(4):181-3. doi: 10.4314/eamj.v79i4.8874. PMID: 12625671.
2. https://applications.emro.who.int/imemrf/Sci_Med_J_1991_3_1_171.pdf
3. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2571720/